Conjunctival Intraepithelial Neoplasia in a Patient Presenting with Pigmented Conjunctival Lesion

Winai Chaidaroon; Chutikarn Dejkriengkraikul; Sirawit Isipradit; Nirush Lertprasertsuke

doi:10.1159/000510570

Conjunctival Intraepithelial Neoplasia in a Patient Presenting with Pigmented Conjunctival Lesion

Case Rep Ophthalmol. 2021 Jan 21;12(1):77-82. doi: 10.1159/000510570. eCollection 2021 Jan-Apr.

Authors

Winai Chaidaroon¹, Chutikarn Dejkriengkraikul¹, Sirawit Isipradit¹, Nirush Lertprasertsuke²

Affiliations

¹ Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
² Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Abstract

We report a case of conjunctival intraepithelial neoplasia (CIN) in a patient presenting with the pigmented conjunctival lesion. This study involved a 56-year-old woman that presented with right eye irritation for 1 month. She noticed brownish pigmentation arising from her right nasal conjunctiva and growing slowly over time. Biomicroscopic examination showed a gelatinous pigmented conjunctival mass with feeder vessels. Conjunctival impression cytology (CIC) was done and reported as CIN. Treatment was started with 0.02% mitomycin-C eye drops. The conjunctival lesion responded well to medication. This report shows that CIN can manifest as a pigmented tumor, resembling melanoma. CIC plays a role in the diagnosis of this condition. This tumor responded well with 0.02% mitomycin-C eye drops.

Keywords: Conjunctival intraepithelial neoplasia; Conjunctival melanoma; Pigmented conjunctival lesion.

Publication types

Case Reports