Kocuria Endophthalmitis: Clinical Spectrum and Long-term Outcomes

Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1768-1774. doi: 10.1080/09273948.2021.1951304. Epub 2021 Jul 20.

Abstract

Purpose: To expand the knowledge regarding the clinical presentation of Kocuria endophthalmitis.

Methods: We included six cases of Kocuria endophthalmitis between January 2018 and December 2020. From all cases, we collected general demographic data, relevant medical, ophthalmological history, microbiological and antibiotic sensitivity results. All cases had a minimum follow-up of 9 months. All cases were treated with intravitreal moxifloxacin and dexamethasone and pars plana vitrectomy. Undiluted vitreous, corneal, conjunctival, and aqueous samples were cultured and analyzed with the Vitek 2 system.

Results: The prevalence of Kocuria endophthalmitis was 6%. (95%CI: 2.26%-12.73%). The mean age at diagnosis was 60.5 ± 15.5 years. All patients had poor visual acuity, severe pain, and severe conjunctival hyperemia at diagnosis. Only one case had a significant improvement in visual acuity at the end of the follow-up.

Conclusion: Kocuria spp are an emerging cause of endophthalmitis and should be considered as part of the differential diagnosis.

Keywords: Endophthalmitis; antibiotic resistance; clinical manifestation; kocuria; outcomes; vitrectomy.

MeSH terms

  • Aged
  • Humans
  • Middle Aged