Purpose: Radiation has been used in the treatment of retinoblastoma. Herein, we present the novel use of palladium-103 plaque brachytherapy as primary treatment.
Observation: An 8-year-old asymptomatic girl presented was found to have a solitary peripheral retinoblastoma in her right eye. She was treated with primary palladium-103 plaque brachytherapy (47.4 Gray over 5 consecutive days). A secondary, vitreous hemorrhage noted 46 months after irradiation was successfully controlled by laser tumor-demarcation. With 19-years follow up, there has been no clinical scleropathy, or local tumor recurrence. The eye yields 20/20 vision and there has been no systemic metastasis.
Conclusion and importance: Palladium-103 plaque brachytherapy successfully controlled retinoblastoma, while preserving the globe, vision, and life.
Keywords: 103Pd, palladium-103; 106Ru, ruthenium-106; 192Ir, iridium-192; 60Co, cobalt-60; AAPM, American Society of Physicists in Medicine; ABS, American Brachytherapy Society; Brachytherapy; EBRT, external beam radiation therapy; Gy, Gray; OCT, optical coherence tomography; Palladium-103; Plaque; RB, retinoblastoma; Retinoblastoma; Survival; TTT, transpupillary thermotherapy; Visual acuity.
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