Atypical Event Profiling of Intra-Arterial Chemotherapy

Austin Bach; Victor M Villegas; Aaron S Gold; Timothy G Murray

doi:10.1177/24741264221083411

Atypical Event Profiling of Intra-Arterial Chemotherapy

J Vitreoretin Dis. 2022 May 20;6(3):251-254. doi: 10.1177/24741264221083411. eCollection 2022 May-Jun.

Authors

Austin Bach^{1

2}, Victor M Villegas³, Aaron S Gold⁴, Timothy G Murray⁴

Affiliations

¹ Nova Southeastern University/Larkin Community Hospital, Miami, FL, USA.
² University of South Florida Morsani College of Medicine, Tampa, FL, USA.
³ Department of Ophthalmology, University of Puerto Rico, San Juan, PR, USA.
⁴ Murray Ocular Oncology & Retina, Miami, FL, USA.

Abstract

Purpose: Three cases of atypical events following intra-arterial chemotherapy for the treatment of retinoblastoma are presented.

Methods: Case report.

Results: One patient had acute orbital swelling with proptosis, another with extravasation of the chemotherapeutic agent, and the final with total ipsilateral hearing loss.

Conclusions: These cases underscore the importance of maintaining close follow-up when using intra-arterial chemotherapy for treatment of retinoblastoma.

Keywords: chemotherapy atypical events; intra-arterial chemotherapy; melphalan; retinoblastoma.

Publication types

Case Reports