Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report

BMC Cardiovasc Disord. 2023 May 16;23(1):253. doi: 10.1186/s12872-023-03284-x.

Abstract

Background: ST elevation myocardial infarction is defined as acute myocardial injury with necrosis due to myocardial ischemia. The frequent cause is thrombotic occlusion of atherosclerotic coronary arteries. In particular situations, thromboembolism can cause myocardial infarction in patients with normal coronary arteries.

Case presentation: We report a particular case of myocardial infarction in a young, previously healthy patient with non-atherosclerotic coronary arteries and inflammatory bowel disease. Although we performed an extensive work up, no clear pathophysiological cause could be diagnosed. Most likely, myocardial infarction was associated with a hypercoagulative state related to systemic inflammation.

Conclusion: The mechanisms of coagulation disturbances in the context of acute and chronic inflammation are not yet fully understood. A better understanding of cardiovascular events in patients with inflammatory bowel disease might lead to new treatment approaches of cardiovascular disease.

Keywords: Case report; Inflammation; Inflammatory Bowel Disease; MINOCA; Myocardial Infarction; STEMI.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Coronary Angiography
  • Coronary Artery Disease* / complications
  • Coronary Artery Disease* / diagnostic imaging
  • Humans
  • Inflammation
  • Inflammatory Bowel Diseases*
  • Myocardial Infarction* / diagnosis
  • Myocardial Infarction* / etiology
  • Myocardial Infarction* / therapy
  • Myocardial Ischemia*