Evaluation of the in vitro and in vivo efficiency of in-feed bacteriophage cocktail application to control Salmonella Typhimurium and Salmonella Enteritidis infection in broiler chicks

Amir Hossein Pourabadeh; Seyed Ahmad Madani; Ruhollah Dorostkar; Mohammad Rezaeian; Hossein Esmaeili; Masoumeh Bolandian; Ali Salavati; Seyed Mohammad Mahdi Hashemian; Arezoo Aghahasani

doi:10.1080/03079457.2024.2304628

Evaluation of the in vitro and in vivo efficiency of in-feed bacteriophage cocktail application to control Salmonella Typhimurium and Salmonella Enteritidis infection in broiler chicks

Avian Pathol. 2024 Jun;53(3):174-181. doi: 10.1080/03079457.2024.2304628. Epub 2024 Jan 25.

Authors

Amir Hossein Pourabadeh¹, Seyed Ahmad Madani¹, Ruhollah Dorostkar², Mohammad Rezaeian¹, Hossein Esmaeili³, Masoumeh Bolandian², Ali Salavati⁴, Seyed Mohammad Mahdi Hashemian⁵, Arezoo Aghahasani²

Affiliations

¹ Department of Animal and Poultry Health and Nutrition, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
² Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
³ Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
⁴ Department of Avian Diseases, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
⁵ Central Veterinary Laboratory, Tehran, Iran.

PMID: 38206101
DOI: 10.1080/03079457.2024.2304628

Abstract

Bacteriophage (BP) cocktail was partially resistant to different temperatures and pH values.The BP cocktail showed lytic effects on different Salmonella isolates.The BP cocktail reduced Salmonella colonization in the internal organs of broilers.

Keywords: Bacteriophage; Salmonella Enteritidis; Salmonella Typhimurium; broiler chicken; feed contamination; salmonellosis.

MeSH terms

Animals
Bacteriophages*
Chickens
Poultry Diseases* / prevention & control
Salmonella Infections, Animal* / prevention & control
Salmonella enteritidis
Salmonella typhimurium