Generation of New Synthons for Synthesis Through Activation of Nitromethane

Wenxuan Wang; Lixing Zhao; Yuexia Zhang

doi:10.1002/cssc.202400454

Generation of New Synthons for Synthesis Through Activation of Nitromethane

ChemSusChem. 2024 May 3:e202400454. doi: 10.1002/cssc.202400454. Online ahead of print.

Authors

Wenxuan Wang¹, Lixing Zhao², Yuexia Zhang³

Affiliations

¹ Ningxia University - North Campus, School of Ecology and Environment, CHINA.
² Qingdao University, College of Chemistry and Chemical Engineering, CHINA.
³ Qingdao University, College of Chemistry and Chemical Engineering, 308 Ningxia Road, , 266071, Qingdao, CHINA.

PMID: 38702899
DOI: 10.1002/cssc.202400454

Abstract

Nitromethane is used a common solvent, stabilizer, and fuel additive. Nitromethane has also been used as a sustainable building block and convenient reagent in chemical synthesis. In this Minireview, we summarize the recent advances in activation of nitromethane, using nitromethane as the source of cyano group, nitrogen, methylamine, formyl group, C1, nitroso, and oxime.

Keywords: nitromethane * activation * cyano group * nitrogen source * C1 source.