Infected Thrombosis Leading to Veno-Venous Extracorporeal Membrane Oxygenation Dysfunction in Chronic Thromboembolic Pulmonary Hypertension

Jeremy C Grate; Tyler S Reynolds; Adam C Gordon; Sagar B Dave

doi:10.1097/MAT.0000000000002233

Infected Thrombosis Leading to Veno-Venous Extracorporeal Membrane Oxygenation Dysfunction in Chronic Thromboembolic Pulmonary Hypertension

ASAIO J. 2024 May 17. doi: 10.1097/MAT.0000000000002233. Online ahead of print.

Authors

Jeremy C Grate¹, Tyler S Reynolds², Adam C Gordon³, Sagar B Dave⁴

Affiliations

¹ From the Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota.
² Department of Surgery, Mike O'Callaghan Military Medical Center, Nellis Air Force Base, Nevada.
³ Department of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia.
⁴ Department of Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia.

PMID: 38753559
DOI: 10.1097/MAT.0000000000002233

Abstract

Nosocomial infections and thrombosis are frequent complications during extracorporeal membrane oxygenation (ECMO). Preventative measures and close monitoring for early recognition of these complications are imperative in patients supported with ECMO. We report the case of a 41 year old female on veno-venous ECMO awaiting surgical thrombectomy for chronic thromboembolic pulmonary hypertension that developed profound bacteremia leading to gross purulence and thrombosis of the membrane oxygenator. Recannulation in addition to targeted antibiotics, frequent cultures, imaging, and surgery were diagnostic and therapeutic interventions that led to ultimate resolution.