Molecular typing and haplotypic associations of HLA-B*44 subtypes

Eur J Immunogenet. 1995 Apr;22(2):215-20. doi: 10.1111/j.1744-313x.1995.tb00233.x.

Abstract

The heterogeneity of HLA-B44 is confirmed and the sequence difference between the two major subtypes, B*4402, *4403, is attributed to one polymorphic site in the third exon. A method is described to discriminate B*4402 and B*4403, and the occurrence and linkage disequilibrium of B*44 subtypes is discussed. No example of B*4401 polymorphism in exon 2 was observed.

Publication types

  • Comparative Study

MeSH terms

  • Alleles*
  • Base Sequence
  • Exons / genetics
  • Genes, MHC Class I*
  • HLA-B Antigens / classification
  • HLA-B Antigens / genetics*
  • HLA-B44 Antigen
  • Haplotypes / genetics*
  • Humans
  • Molecular Sequence Data
  • Sequence Alignment
  • Sequence Homology, Nucleic Acid

Substances

  • HLA-B Antigens
  • HLA-B44 Antigen