Purpose/methods: We studied a case in which a streptokinase-induced Tenon's hemorrhage developed after retinal detachment surgery. The patient received intravenous streptokinase for myocardial infarction two hours after pars plana vitrectomy and encircling scleral buckling surgery.
Results/conclusions: A Tenon's hemorrhage with an orbital compartment syndrome developed in the patient's left eye, and he underwent lateral canthotomy and inferior cantholysis. Symptoms of the compartment syndrome resolved and final visual acuity was 20/40. Although there are potential ocular-related side effects to thrombolytic therapy, there has been no permanent ocular morbidity reported after thrombolytic-related hemorrhage. We recommend not to defer such life-saving therapy after ocular surgery.