The "pseudo-CSF" signal of orbital optic glioma on magnetic resonance imaging: a signature of neurofibromatosis

Surv Ophthalmol. 1993 Sep-Oct;38(2):213-8. doi: 10.1016/0039-6257(93)90104-f.

Abstract

A five-and-a-half-year-old boy with neurofibromatosis had bilateral orbital optic gliomas visible on magnetic resonance imaging. Both tumors displayed a double-intensity signal characterized by a circumferential area of CSF-intensity tissue surrounding and sharply delimited from a central linear core of opposite signal intensity. The peripheral CSF-intensity signal in orbital optic glioma correlates with the histopathological finding of perineural arachnoidal gliomatosis and serves as a neuroradiologic marker for neurofibromatosis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • Cranial Nerve Neoplasms / diagnosis*
  • Glioma / diagnosis*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neurofibromatoses / diagnosis*
  • Optic Nerve Diseases / diagnosis*
  • Orbital Neoplasms / diagnosis*