Comparative evaluation of different surgical approach for the treatment of pterygium with the respect on recurrence, time interval to the recurrence and postoperative complications is done. Only 6% of recurrence were found using buccal mucosal flap as the first surgery, but when the same approach is used for recurrence number of retreatment is similar to the other technique-transpositional slide flap. 5-Fluorouracil as additional therapy decreased the number of recurrence without increasing of complications.