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A single-dose comparison of the acute effects between the new somatostatin analog SOM230 and octreotide in acromegalic patients.
van der Hoek J, de Herder WW, Feelders RA, van der Lely AJ, Uitterlinden P, Boerlin V, Bruns C, Poon KW, Lewis I, Weckbecker G, Krahnke T, Hofland LJ, Lamberts SW. van der Hoek J, et al. Among authors: weckbecker g. J Clin Endocrinol Metab. 2004 Feb;89(2):638-45. doi: 10.1210/jc.2003-031052. J Clin Endocrinol Metab. 2004. PMID: 14764775 Free article. Clinical Trial.
The novel somatostatin analog SOM230 is a potent inhibitor of hormone release by growth hormone- and prolactin-secreting pituitary adenomas in vitro.
Hofland LJ, van der Hoek J, van Koetsveld PM, de Herder WW, Waaijers M, Sprij-Mooij D, Bruns C, Weckbecker G, Feelders R, van der Lely AJ, Beckers A, Lamberts SW. Hofland LJ, et al. Among authors: weckbecker g. J Clin Endocrinol Metab. 2004 Apr;89(4):1577-85. doi: 10.1210/jc.2003-031344. J Clin Endocrinol Metab. 2004. PMID: 15070915 Free article.
The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5.
Hofland LJ, van der Hoek J, Feelders R, van Aken MO, van Koetsveld PM, Waaijers M, Sprij-Mooij D, Bruns C, Weckbecker G, de Herder WW, Beckers A, Lamberts SW. Hofland LJ, et al. Among authors: weckbecker g. Eur J Endocrinol. 2005 Apr;152(4):645-54. doi: 10.1530/eje.1.01876. Eur J Endocrinol. 2005. PMID: 15817922 Free article.
SOM230: a new therapeutic modality for Cushing's disease.
Lewis I, Schmid HA, Kneuer R, Hoyer D, Silva AP, Weckbecker G, Bruns C, Pless J. Lewis I, et al. Among authors: weckbecker g. Chimia (Aarau). 2014;68(7-8):483-4. doi: 10.2533/chimia.2014.483. Chimia (Aarau). 2014. PMID: 25437387 Free article.
82 results