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Structural basis for complement factor H linked age-related macular degeneration.
Prosser BE, Johnson S, Roversi P, Herbert AP, Blaum BS, Tyrrell J, Jowitt TA, Clark SJ, Tarelli E, Uhrín D, Barlow PN, Sim RB, Day AJ, Lea SM. Prosser BE, et al. Among authors: lea sm. J Exp Med. 2007 Oct 1;204(10):2277-83. doi: 10.1084/jem.20071069. Epub 2007 Sep 24. J Exp Med. 2007. PMID: 17893204 Free PMC article.
An atomic resolution model for assembly, architecture, and function of the Dr adhesins.
Anderson KL, Billington J, Pettigrew D, Cota E, Simpson P, Roversi P, Chen HA, Urvil P, du Merle L, Barlow PN, Medof ME, Smith RA, Nowicki B, Le Bouguénec C, Lea SM, Matthews S. Anderson KL, et al. Among authors: lea sm. Mol Cell. 2004 Aug 27;15(4):647-57. doi: 10.1016/j.molcel.2004.08.003. Mol Cell. 2004. PMID: 15327779 Free article.
Putting the structure into complement.
Lea SM, Johnson S. Lea SM, et al. Immunobiology. 2012 Nov;217(11):1117-21. doi: 10.1016/j.imbio.2012.07.005. Immunobiology. 2012. PMID: 22964238 Free PMC article. Review.
Complement factor I in health and disease.
Nilsson SC, Sim RB, Lea SM, Fremeaux-Bacchi V, Blom AM. Nilsson SC, et al. Among authors: lea sm. Mol Immunol. 2011 Aug;48(14):1611-20. doi: 10.1016/j.molimm.2011.04.004. Epub 2011 Apr 29. Mol Immunol. 2011. PMID: 21529951 Review.
Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6-8.
Prosser BE, Johnson S, Roversi P, Clark SJ, Tarelli E, Sim RB, Day AJ, Lea SM. Prosser BE, et al. Among authors: lea sm. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jun 1;63(Pt 6):480-3. doi: 10.1107/S1744309107020052. Epub 2007 May 5. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17554167 Free PMC article.
Structure of human complement C8, a precursor to membrane attack.
Bubeck D, Roversi P, Donev R, Morgan BP, Llorca O, Lea SM. Bubeck D, et al. Among authors: lea sm. J Mol Biol. 2011 Jan 14;405(2):325-30. doi: 10.1016/j.jmb.2010.10.031. Epub 2010 Nov 10. J Mol Biol. 2011. PMID: 21073882 Free PMC article.
175 results