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Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
Myocardial Infarction Genetics Consortium; Kathiresan S, Voight BF, Purcell S, Musunuru K, Ardissino D, Mannucci PM, Anand S, Engert JC, Samani NJ, Schunkert H, Erdmann J, Reilly MP, Rader DJ, Morgan T, Spertus JA, Stoll M, Girelli D, McKeown PP, Patterson CC, Siscovick DS, O'Donnell CJ, Elosua R, Peltonen L, Salomaa V, Schwartz SM, Melander O, Altshuler D, Ardissino D, Merlini PA, Berzuini C, Bernardinelli L, Peyvandi F, Tubaro M, Celli P, Ferrario M, Fetiveau R, Marziliano N, Casari G, Galli M, Ribichini F, Rossi M, Bernardi F, Zonzin P, Piazza A, Mannucci PM, Schwartz SM, Siscovick DS, Yee J, Friedlander Y, Elosua R, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Kathiresan S, Meigs JB, Williams G, Nathan DM, MacRae CA, O'Donnell CJ, Salomaa V, Havulinna AS, Peltonen L, Melander O, Berglund G, Voight BF, Kathiresan S, Hirschhorn JN, Asselta R, Duga S, Spreafico M, Musunuru K, Daly MJ, Purcell S, Voight BF, Purcell S, Nemesh J, Korn JM, McCarroll SA, Schwartz SM, Yee J, Kathiresan S, Lucas G, Subirana I, Elosua R, Surti A, Guiducci C, Gianniny L, Mirel D, Parkin M, Burtt N, Gabriel SB, Samani NJ, Thompson JR, Braund PS, Wright BJ, Balmforth AJ, Ball SG, Hall A; … See abstract for full author list ➔ Myocardial Infarction Genetics Consortium, et al. Among authors: musunuru k. Nat Genet. 2009 Mar;41(3):334-41. doi: 10.1038/ng.327. Epub 2009 Feb 8. Nat Genet. 2009. PMID: 19198609 Free PMC article.
GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy.
Kasiewicz LN, Biswas S, Beach A, Ren H, Dutta C, Mazzola AM, Rohde E, Chadwick A, Cheng C, Garcia SP, Iyer S, Matsumoto Y, Khera AV, Musunuru K, Kathiresan S, Malyala P, Rajeev KG, Bellinger AM. Kasiewicz LN, et al. Among authors: musunuru k. Nat Commun. 2023 May 15;14(1):2776. doi: 10.1038/s41467-023-37465-1. Nat Commun. 2023. PMID: 37188660 Free PMC article.
Response to Harding and Martinez.
Brooks DL, Musunuru K, Wang X. Brooks DL, et al. Among authors: musunuru k. HGG Adv. 2024 May 14;5(3):100307. doi: 10.1016/j.xhgg.2024.100307. Online ahead of print. HGG Adv. 2024. PMID: 38796849 Free article. No abstract available.
Improved specificity and efficacy of base-editing therapies with hybrid guide RNAs.
Whittaker MN, Brooks DL, Quigley A, Jindal I, Qu P, Wang JZ, Ahrens-Nicklas RC, Musunuru K, Alameh MG, Peranteau WH, Wang X. Whittaker MN, et al. Among authors: musunuru k. bioRxiv [Preprint]. 2024 Apr 23:2024.04.22.590531. doi: 10.1101/2024.04.22.590531. bioRxiv. 2024. PMID: 38712058 Free PMC article. Preprint.
Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes.
Whittaker MN, Testa LC, Quigley A, Jindal I, Cortez-Alvarado SV, Qu P, Yang Y, Alameh MG, Musunuru K, Wang X. Whittaker MN, et al. Among authors: musunuru k. Arterioscler Thromb Vasc Biol. 2023 Oct;43(10):2075-2077. doi: 10.1161/ATVBAHA.123.319748. Epub 2023 Aug 17. Arterioscler Thromb Vasc Biol. 2023. PMID: 37589141 No abstract available.
227 results