Peterson JR - Search Results

1

PAK kinase regulates Rac GTPase and is a potential target in human schwannomas.

Flaiz C, Chernoff J, Ammoun S, Peterson JR, Hanemann CO. Flaiz C, et al. Among authors: peterson jr. Exp Neurol. 2009 Jul;218(1):137-44. doi: 10.1016/j.expneurol.2009.04.019. Epub 2009 May 3. Exp Neurol. 2009. PMID: 19409384 Free PMC article.

2

An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase.

Deacon SW, Beeser A, Fukui JA, Rennefahrt UE, Myers C, Chernoff J, Peterson JR. Deacon SW, et al. Among authors: peterson jr. Chem Biol. 2008 Apr;15(4):322-31. doi: 10.1016/j.chembiol.2008.03.005. Chem Biol. 2008. PMID: 18420139 Free PMC article.

3

Group I p21-activated kinases (PAKs) promote tumor cell proliferation and survival through the AKT1 and Raf-MAPK pathways.

Menges CW, Sementino E, Talarchek J, Xu J, Chernoff J, Peterson JR, Testa JR. Menges CW, et al. Among authors: peterson jr. Mol Cancer Res. 2012 Sep;10(9):1178-88. doi: 10.1158/1541-7786.MCR-12-0082. Epub 2012 Jul 12. Mol Cancer Res. 2012. PMID: 22798428 Free PMC article.

4

Specificity profiling of Pak kinases allows identification of novel phosphorylation sites.

Rennefahrt UE, Deacon SW, Parker SA, Devarajan K, Beeser A, Chernoff J, Knapp S, Turk BE, Peterson JR. Rennefahrt UE, et al. Among authors: peterson jr. J Biol Chem. 2007 May 25;282(21):15667-78. doi: 10.1074/jbc.M700253200. Epub 2007 Mar 28. J Biol Chem. 2007. PMID: 17392278 Free article.

5

Src transforms in a Cool way.

Peterson JR, Chernoff J. Peterson JR, et al. Nat Cell Biol. 2006 Sep;8(9):905-7. doi: 10.1038/ncb0906-905. Nat Cell Biol. 2006. PMID: 16946737 No abstract available.

6

Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration.

Delorme-Walker VD, Peterson JR, Chernoff J, Waterman CM, Danuser G, DerMardirossian C, Bokoch GM. Delorme-Walker VD, et al. Among authors: peterson jr. J Cell Biol. 2011 Jun 27;193(7):1289-303. doi: 10.1083/jcb.201010059. J Cell Biol. 2011. PMID: 21708980 Free PMC article.

7

The tumor suppressor Mst1 promotes changes in the cellular redox state by phosphorylation and inactivation of peroxiredoxin-1 protein.

Rawat SJ, Creasy CL, Peterson JR, Chernoff J. Rawat SJ, et al. Among authors: peterson jr. J Biol Chem. 2013 Mar 22;288(12):8762-8771. doi: 10.1074/jbc.M112.414524. Epub 2013 Feb 5. J Biol Chem. 2013. PMID: 23386615 Free PMC article.

8

Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer.

Kurimchak AM, Shelton C, Duncan KE, Johnson KJ, Brown J, O'Brien S, Gabbasov R, Fink LS, Li Y, Lounsbury N, Abou-Gharbia M, Childers WE, Connolly DC, Chernoff J, Peterson JR, Duncan JS. Kurimchak AM, et al. Among authors: peterson jr. Cell Rep. 2016 Aug 2;16(5):1273-1286. doi: 10.1016/j.celrep.2016.06.091. Epub 2016 Jul 21. Cell Rep. 2016. PMID: 27452461 Free PMC article.

9

Chemical inhibition through conformational stabilization of Rho GTPase effectors.

Deacon SW, Peterson JR. Deacon SW, et al. Among authors: peterson jr. Handb Exp Pharmacol. 2008;(186):431-60. doi: 10.1007/978-3-540-72843-6_18. Handb Exp Pharmacol. 2008. PMID: 18491063 Review.

10

An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently.

Viaud J, Peterson JR. Viaud J, et al. Among authors: peterson jr. Mol Cancer Ther. 2009 Sep;8(9):2559-65. doi: 10.1158/1535-7163.MCT-09-0102. Epub 2009 Sep 1. Mol Cancer Ther. 2009. PMID: 19723886 Free PMC article.

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