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Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin.
Valleix S, Gillmore JD, Bridoux F, Mangione PP, Dogan A, Nedelec B, Boimard M, Touchard G, Goujon JM, Lacombe C, Lozeron P, Adams D, Lacroix C, Maisonobe T, Planté-Bordeneuve V, Vrana JA, Theis JD, Giorgetti S, Porcari R, Ricagno S, Bolognesi M, Stoppini M, Delpech M, Pepys MB, Hawkins PN, Bellotti V. Valleix S, et al. Among authors: ricagno s. N Engl J Med. 2012 Jun 14;366(24):2276-83. doi: 10.1056/NEJMoa1201356. N Engl J Med. 2012. PMID: 22693999 Free article.
The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties.
Esposito G, Ricagno S, Corazza A, Rennella E, Gümral D, Mimmi MC, Betto E, Pucillo CE, Fogolari F, Viglino P, Raimondi S, Giorgetti S, Bolognesi B, Merlini G, Stoppini M, Bolognesi M, Bellotti V. Esposito G, et al. Among authors: ricagno s. J Mol Biol. 2008 May 9;378(4):887-97. doi: 10.1016/j.jmb.2008.03.002. Epub 2008 Mar 8. J Mol Biol. 2008. PMID: 18395224
The effects of an ideal beta-turn on beta-2 microglobulin fold stability.
Colombo M, Ricagno S, Barbiroli A, Santambrogio C, Giorgetti S, Raimondi S, Bonomi F, Grandori R, Bellotti V, Bolognesi M. Colombo M, et al. Among authors: ricagno s. J Biochem. 2011 Jul;150(1):39-47. doi: 10.1093/jb/mvr034. Epub 2011 Mar 11. J Biochem. 2011. PMID: 21398368
D-strand perturbation and amyloid propensity in beta-2 microglobulin.
Azinas S, Colombo M, Barbiroli A, Santambrogio C, Giorgetti S, Raimondi S, Bonomi F, Grandori R, Bellotti V, Ricagno S, Bolognesi M. Azinas S, et al. Among authors: ricagno s. FEBS J. 2011 Jul;278(13):2349-58. doi: 10.1111/j.1742-4658.2011.08157.x. Epub 2011 May 31. FEBS J. 2011. PMID: 21569201 Free article.
The two tryptophans of β2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure.
Raimondi S, Barbarini N, Mangione P, Esposito G, Ricagno S, Bolognesi M, Zorzoli I, Marchese L, Soria C, Bellazzi R, Monti M, Stoppini M, Stefanelli M, Magni P, Bellotti V. Raimondi S, et al. Among authors: ricagno s. BMC Evol Biol. 2011 Jun 10;11:159. doi: 10.1186/1471-2148-11-159. BMC Evol Biol. 2011. PMID: 21663612 Free PMC article.
83 results