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Identification of a SIRT1 mutation in a family with type 1 diabetes.
Biason-Lauber A, Böni-Schnetzler M, Hubbard BP, Bouzakri K, Brunner A, Cavelti-Weder C, Keller C, Meyer-Böni M, Meier DT, Brorsson C, Timper K, Leibowitz G, Patrignani A, Bruggmann R, Boily G, Zulewski H, Geier A, Cermak JM, Elliott P, Ellis JL, Westphal C, Knobel U, Eloranta JJ, Kerr-Conte J, Pattou F, Konrad D, Matter CM, Fontana A, Rogler G, Schlapbach R, Regairaz C, Carballido JM, Glaser B, McBurney MW, Pociot F, Sinclair DA, Donath MY. Biason-Lauber A, et al. Among authors: mcburney mw. Cell Metab. 2013 Mar 5;17(3):448-455. doi: 10.1016/j.cmet.2013.02.001. Cell Metab. 2013. PMID: 23473037 Free PMC article.
sirt1-null mice develop an autoimmune-like condition.
Sequeira J, Boily G, Bazinet S, Saliba S, He X, Jardine K, Kennedy C, Staines W, Rousseaux C, Mueller R, McBurney MW. Sequeira J, et al. Among authors: mcburney mw. Exp Cell Res. 2008 Oct 1;314(16):3069-74. doi: 10.1016/j.yexcr.2008.07.011. Epub 2008 Jul 23. Exp Cell Res. 2008. PMID: 18687325
SIRT1 is essential for normal cognitive function and synaptic plasticity.
Michán S, Li Y, Chou MM, Parrella E, Ge H, Long JM, Allard JS, Lewis K, Miller M, Xu W, Mervis RF, Chen J, Guerin KI, Smith LE, McBurney MW, Sinclair DA, Baudry M, de Cabo R, Longo VD. Michán S, et al. Among authors: mcburney mw. J Neurosci. 2010 Jul 21;30(29):9695-707. doi: 10.1523/JNEUROSCI.0027-10.2010. J Neurosci. 2010. PMID: 20660252 Free PMC article.
SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis.
Stein S, Lohmann C, Schäfer N, Hofmann J, Rohrer L, Besler C, Rothgiesser KM, Becher B, Hottiger MO, Borén J, McBurney MW, Landmesser U, Lüscher TF, Matter CM. Stein S, et al. Among authors: mcburney mw. Eur Heart J. 2010 Sep;31(18):2301-9. doi: 10.1093/eurheartj/ehq107. Epub 2010 Apr 23. Eur Heart J. 2010. PMID: 20418343 Free PMC article.
Mammalian SIRT1 represses forkhead transcription factors.
Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, Bultsma Y, McBurney M, Guarente L. Motta MC, et al. Cell. 2004 Feb 20;116(4):551-63. doi: 10.1016/s0092-8674(04)00126-6. Cell. 2004. PMID: 14980222 Free article.
SirT1 fails to affect p53-mediated biological functions.
Kamel C, Abrol M, Jardine K, He X, McBurney MW. Kamel C, et al. Among authors: mcburney mw. Aging Cell. 2006 Feb;5(1):81-8. doi: 10.1111/j.1474-9726.2006.00191.x. Aging Cell. 2006. PMID: 16441846 Free article.
SirT1 regulates energy metabolism and response to caloric restriction in mice.
Boily G, Seifert EL, Bevilacqua L, He XH, Sabourin G, Estey C, Moffat C, Crawford S, Saliba S, Jardine K, Xuan J, Evans M, Harper ME, McBurney MW. Boily G, et al. Among authors: mcburney mw. PLoS One. 2008 Mar 12;3(3):e1759. doi: 10.1371/journal.pone.0001759. PLoS One. 2008. PMID: 18335035 Free PMC article.
173 results