Wekerle H - Search Results

1

The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.

Hoffmann FS, Kuhn PH, Laurent SA, Hauck SM, Berer K, Wendlinger SA, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister HW, Alexander T, Hiepe F, Kümpfel T, Crawford HC, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E. Hoffmann FS, et al. Among authors: wekerle h. J Immunol. 2015 Jan 15;194(2):542-52. doi: 10.4049/jimmunol.1402070. Epub 2014 Dec 10. J Immunol. 2015. PMID: 25505277 Free PMC article. Clinical Trial.

2

B cells in spontaneous autoimmune diseases of the central nervous system.

Berer K, Wekerle H, Krishnamoorthy G. Berer K, et al. Among authors: wekerle h. Mol Immunol. 2011 Jun;48(11):1332-7. doi: 10.1016/j.molimm.2010.10.025. Epub 2010 Dec 13. Mol Immunol. 2011. PMID: 21146219 Review.

3

γ-Secretase directly sheds the survival receptor BCMA from plasma cells.

Laurent SA, Hoffmann FS, Kuhn PH, Cheng Q, Chu Y, Schmidt-Supprian M, Hauck SM, Schuh E, Krumbholz M, Rübsamen H, Wanngren J, Khademi M, Olsson T, Alexander T, Hiepe F, Pfister HW, Weber F, Jenne D, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E. Laurent SA, et al. Among authors: wekerle h. Nat Commun. 2015 Jun 11;6:7333. doi: 10.1038/ncomms8333. Nat Commun. 2015. PMID: 26065893 Free PMC article.

4

BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma.

Krumbholz M, Theil D, Derfuss T, Rosenwald A, Schrader F, Monoranu CM, Kalled SL, Hess DM, Serafini B, Aloisi F, Wekerle H, Hohlfeld R, Meinl E. Krumbholz M, et al. Among authors: wekerle h. J Exp Med. 2005 Jan 17;201(2):195-200. doi: 10.1084/jem.20041674. Epub 2005 Jan 10. J Exp Med. 2005. PMID: 15642740 Free PMC article.

5

Drug insight: using monoclonal antibodies to treat multiple sclerosis.

Hohlfeld R, Wekerle H. Hohlfeld R, et al. Among authors: wekerle h. Nat Clin Pract Neurol. 2005 Nov;1(1):34-44. doi: 10.1038/ncpneuro0016. Nat Clin Pract Neurol. 2005. PMID: 16932490 Review.

6

Beneficial brain autoimmunity?

Wekerle H, Hohlfeld R. Wekerle H, et al. Brain. 2010 Aug;133(Pt 8):2182-4. doi: 10.1093/brain/awq206. Brain. 2010. PMID: 20826427 No abstract available.

7

Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases.

Mayer MC, Breithaupt C, Reindl M, Schanda K, Rostásy K, Berger T, Dale RC, Brilot F, Olsson T, Jenne D, Pröbstel AK, Dornmair K, Wekerle H, Hohlfeld R, Banwell B, Bar-Or A, Meinl E. Mayer MC, et al. Among authors: wekerle h. J Immunol. 2013 Oct 1;191(7):3594-604. doi: 10.4049/jimmunol.1301296. Epub 2013 Sep 6. J Immunol. 2013. PMID: 24014878

8

The search for the target antigens of multiple sclerosis, part 2: CD8+ T cells, B cells, and antibodies in the focus of reverse-translational research.

Hohlfeld R, Dornmair K, Meinl E, Wekerle H. Hohlfeld R, et al. Among authors: wekerle h. Lancet Neurol. 2016 Mar;15(3):317-31. doi: 10.1016/S1474-4422(15)00313-0. Epub 2015 Dec 24. Lancet Neurol. 2016. PMID: 26724102 Review.

9

The search for the target antigens of multiple sclerosis, part 1: autoreactive CD4+ T lymphocytes as pathogenic effectors and therapeutic targets.

Hohlfeld R, Dornmair K, Meinl E, Wekerle H. Hohlfeld R, et al. Among authors: wekerle h. Lancet Neurol. 2016 Feb;15(2):198-209. doi: 10.1016/S1474-4422(15)00334-8. Epub 2015 Dec 24. Lancet Neurol. 2016. PMID: 26724103 Review.

10

Molecular mimicry in multiple sclerosis.

Wekerle H, Hohlfeld R. Wekerle H, et al. N Engl J Med. 2003 Jul 10;349(2):185-6. doi: 10.1056/NEJMcibr035136. N Engl J Med. 2003. PMID: 12853593 Review. No abstract available.

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