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γ-Secretase directly sheds the survival receptor BCMA from plasma cells.
Laurent SA, Hoffmann FS, Kuhn PH, Cheng Q, Chu Y, Schmidt-Supprian M, Hauck SM, Schuh E, Krumbholz M, Rübsamen H, Wanngren J, Khademi M, Olsson T, Alexander T, Hiepe F, Pfister HW, Weber F, Jenne D, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E. Laurent SA, et al. Among authors: hohlfeld r. Nat Commun. 2015 Jun 11;6:7333. doi: 10.1038/ncomms8333. Nat Commun. 2015. PMID: 26065893 Free PMC article.
The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.
Hoffmann FS, Kuhn PH, Laurent SA, Hauck SM, Berer K, Wendlinger SA, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister HW, Alexander T, Hiepe F, Kümpfel T, Crawford HC, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E. Hoffmann FS, et al. Among authors: hohlfeld r. J Immunol. 2015 Jan 15;194(2):542-52. doi: 10.4049/jimmunol.1402070. Epub 2014 Dec 10. J Immunol. 2015. PMID: 25505277 Free PMC article. Clinical Trial.
Oligodendrocyte myelin glycoprotein as a novel target for pathogenic autoimmunity in the CNS.
Gerhards R, Pfeffer LK, Lorenz J, Starost L, Nowack L, Thaler FS, Schlüter M, Rübsamen H, Macrini C, Winklmeier S, Mader S, Bronge M, Grönlund H, Feederle R, Hsia HE, Lichtenthaler SF, Merl-Pham J, Hauck SM, Kuhlmann T, Bauer IJ, Beltran E, Gerdes LA, Mezydlo A, Bar-Or A, Banwell B, Khademi M, Olsson T, Hohlfeld R, Lassmann H, Kümpfel T, Kawakami N, Meinl E. Gerhards R, et al. Among authors: hohlfeld r. Acta Neuropathol Commun. 2020 Nov 30;8(1):207. doi: 10.1186/s40478-020-01086-2. Acta Neuropathol Commun. 2020. PMID: 33256847 Free PMC article.
Molecular mimicry in multiple sclerosis.
Wekerle H, Hohlfeld R. Wekerle H, et al. Among authors: hohlfeld r. N Engl J Med. 2003 Jul 10;349(2):185-6. doi: 10.1056/NEJMcibr035136. N Engl J Med. 2003. PMID: 12853593 Review. No abstract available.
431 results