Kulathu Y - Search Results

1

PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.

Hall EA, Nahorski MS, Murray LM, Shaheen R, Perkins E, Dissanayake KN, Kristaryanto Y, Jones RA, Vogt J, Rivagorda M, Handley MT, Mali GR, Quidwai T, Soares DC, Keighren MA, McKie L, Mort RL, Gammoh N, Garcia-Munoz A, Davey T, Vermeren M, Walsh D, Budd P, Aligianis IA, Faqeih E, Quigley AJ, Jackson IJ, Kulathu Y, Jackson M, Ribchester RR, von Kriegsheim A, Alkuraya FS, Woods CG, Maher ER, Mill P. Hall EA, et al. Among authors: kulathu y. Am J Hum Genet. 2017 May 4;100(5):706-724. doi: 10.1016/j.ajhg.2017.03.008. Epub 2017 Apr 13. Am J Hum Genet. 2017. PMID: 28413018 Free PMC article.

2

K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin.

Kristariyanto YA, Abdul Rehman SA, Campbell DG, Morrice NA, Johnson C, Toth R, Kulathu Y. Kristariyanto YA, et al. Among authors: kulathu y. Mol Cell. 2015 Apr 2;58(1):83-94. doi: 10.1016/j.molcel.2015.01.041. Epub 2015 Mar 5. Mol Cell. 2015. PMID: 25752573 Free PMC article.

3

Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages.

Kulathu Y, Komander D. Kulathu Y, et al. Nat Rev Mol Cell Biol. 2012 Jul 23;13(8):508-23. doi: 10.1038/nrm3394. Nat Rev Mol Cell Biol. 2012. PMID: 22820888 Review.

4

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.

Kelsall IR, Kristariyanto YA, Knebel A, Wood NT, Kulathu Y, Alpi AF. Kelsall IR, et al. Among authors: kulathu y. J Biol Chem. 2019 Feb 22;294(8):2651-2664. doi: 10.1074/jbc.RA118.005861. Epub 2018 Dec 26. J Biol Chem. 2019. PMID: 30587576 Free PMC article.

5

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain.

Kulathu Y, Akutsu M, Bremm A, Hofmann K, Komander D. Kulathu Y, et al. Nat Struct Mol Biol. 2009 Dec;16(12):1328-30. doi: 10.1038/nsmb.1731. Epub 2009 Nov 22. Nat Struct Mol Biol. 2009. PMID: 19935683

6

Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs.

Kulathu Y. Kulathu Y. Cell Chem Biol. 2016 Apr 21;23(4):432-4. doi: 10.1016/j.chembiol.2016.04.001. Cell Chem Biol. 2016. PMID: 27105279 Free PMC article.

7

A single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chains.

Kristariyanto YA, Abdul Rehman SA, Weidlich S, Knebel A, Kulathu Y. Kristariyanto YA, et al. Among authors: kulathu y. EMBO Rep. 2017 Mar;18(3):392-402. doi: 10.15252/embr.201643205. Epub 2017 Jan 12. EMBO Rep. 2017. PMID: 28082312 Free PMC article.

8

Mechanisms of regulation and diversification of deubiquitylating enzyme function.

Leznicki P, Kulathu Y. Leznicki P, et al. Among authors: kulathu y. J Cell Sci. 2017 Jun 15;130(12):1997-2006. doi: 10.1242/jcs.201855. Epub 2017 May 5. J Cell Sci. 2017. PMID: 28476940 Review.

9

Linking K29-Ub chains to biology.

Lange SM, Kulathu Y. Lange SM, et al. Among authors: kulathu y. Nat Chem Biol. 2021 Aug;17(8):843-844. doi: 10.1038/s41589-021-00833-3. Nat Chem Biol. 2021. PMID: 34239126 No abstract available.

10

MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes.

Abdul Rehman SA, Kristariyanto YA, Choi SY, Nkosi PJ, Weidlich S, Labib K, Hofmann K, Kulathu Y. Abdul Rehman SA, et al. Among authors: kulathu y. Mol Cell. 2016 Jul 7;63(1):146-55. doi: 10.1016/j.molcel.2016.05.009. Epub 2016 Jun 9. Mol Cell. 2016. PMID: 27292798 Free PMC article.

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