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BHD-associated kidney cancer exhibits unique molecular characteristics and a wide variety of variants in chromatin remodeling genes.
Hasumi H, Furuya M, Tatsuno K, Yamamoto S, Baba M, Hasumi Y, Isono Y, Suzuki K, Jikuya R, Otake S, Muraoka K, Osaka K, Hayashi N, Makiyama K, Miyoshi Y, Kondo K, Nakaigawa N, Kawahara T, Izumi K, Teranishi J, Yumura Y, Uemura H, Nagashima Y, Metwalli AR, Schmidt LS, Aburatani H, Linehan WM, Yao M. Hasumi H, et al. Among authors: isono y. Hum Mol Genet. 2018 Aug 1;27(15):2712-2724. doi: 10.1093/hmg/ddy181. Hum Mol Genet. 2018. PMID: 29767721 Free PMC article.
H255Y and K508R missense mutations in tumour suppressor folliculin (FLCN) promote kidney cell proliferation.
Hasumi H, Hasumi Y, Baba M, Nishi H, Furuya M, Vocke CD, Lang M, Irie N, Esumi C, Merino MJ, Kawahara T, Isono Y, Makiyama K, Warner AC, Haines DC, Wei MH, Zbar B, Hagenau H, Feigenbaum L, Kondo K, Nakaigawa N, Yao M, Metwalli AR, Marston Linehan W, Schmidt LS. Hasumi H, et al. Among authors: isono y. Hum Mol Genet. 2017 Jan 15;26(2):354-366. doi: 10.1093/hmg/ddw392. Hum Mol Genet. 2017. PMID: 28007907 Free PMC article.
FLCN alteration drives metabolic reprogramming towards nucleotide synthesis and cyst formation in salivary gland.
Isono Y, Furuya M, Kuwahara T, Sano D, Suzuki K, Jikuya R, Mitome T, Otake S, Kawahara T, Ito Y, Muraoka K, Nakaigawa N, Kimura Y, Baba M, Nagahama K, Takahata H, Saito I, Schmidt LS, Linehan WM, Kodama T, Yao M, Oridate N, Hasumi H. Isono Y, et al. Biochem Biophys Res Commun. 2020 Feb 19;522(4):931-938. doi: 10.1016/j.bbrc.2019.11.184. Epub 2019 Dec 2. Biochem Biophys Res Commun. 2020. PMID: 31806376 Free PMC article.
Identification of human papillomavirus (HPV) 16 DNA integration and the ensuing patterns of methylation in HPV-associated head and neck squamous cell carcinoma cell lines.
Hatano T, Sano D, Takahashi H, Hyakusoku H, Isono Y, Shimada S, Sawakuma K, Takada K, Oikawa R, Watanabe Y, Yamamoto H, Itoh F, Myers JN, Oridate N. Hatano T, et al. Among authors: isono y. Int J Cancer. 2017 Apr 1;140(7):1571-1580. doi: 10.1002/ijc.30589. Epub 2017 Jan 9. Int J Cancer. 2017. PMID: 28006857 Free PMC article.
Long-term treatment outcome of type 1 thyroplasty using novel titanium medialization laryngoplasty implant combined with arytenoid adduction for unilateral vocal cord paralysis: single-arm interventional study at a single institution.
Sano D, Matsushima K, Isono Y, Ikui Y, Kinutani Y, Chiba Y, Hirose H, Oridate N. Sano D, et al. Among authors: isono y. Laryngoscope Investig Otolaryngol. 2020 Sep 30;5(5):895-902. doi: 10.1002/lio2.462. eCollection 2020 Oct. Laryngoscope Investig Otolaryngol. 2020. PMID: 33134537 Free PMC article.
85 results