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Therapeutic strategies targeting FOXO transcription factors.
Calissi G, Lam EW, Link W. Calissi G, et al. Among authors: link w. Nat Rev Drug Discov. 2021 Jan;20(1):21-38. doi: 10.1038/s41573-020-0088-2. Epub 2020 Nov 10. Nat Rev Drug Discov. 2021. PMID: 33173189 Review.
Introduction to FOXO Biology.
Link W. Link W. Methods Mol Biol. 2019;1890:1-9. doi: 10.1007/978-1-4939-8900-3_1. Methods Mol Biol. 2019. PMID: 30414140 Review.
Screening Health-Promoting Compounds for Their Capacity to Induce the Activity of FOXO3.
Jimenez L, Silva A, Calissi G, Grenho I, Monteiro R, Mayoral-Varo V, Blanco-Aparicio C, Pastor J, Bustos V, Bracher F, Megías D, Ferreira BI, Link W. Jimenez L, et al. Among authors: link w. J Gerontol A Biol Sci Med Sci. 2022 Aug 12;77(8):1485-1493. doi: 10.1093/gerona/glab265. J Gerontol A Biol Sci Med Sci. 2022. PMID: 34508571 Free PMC article.
mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity.
Jimenez L, Amenabar C, Mayoral-Varo V, Mackenzie TA, Ramos MC, Silva A, Calissi G, Grenho I, Blanco-Aparicio C, Pastor J, Megías D, Ferreira BI, Link W. Jimenez L, et al. Among authors: link w. Molecules. 2022 Aug 24;27(17):5414. doi: 10.3390/molecules27175414. Molecules. 2022. PMID: 36080182 Free PMC article.
FOXO transcription factors as therapeutic targets in human diseases.
Orea-Soufi A, Paik J, Bragança J, Donlon TA, Willcox BJ, Link W. Orea-Soufi A, et al. Among authors: link w. Trends Pharmacol Sci. 2022 Dec;43(12):1070-1084. doi: 10.1016/j.tips.2022.09.010. Epub 2022 Oct 21. Trends Pharmacol Sci. 2022. PMID: 36280450 Review.
FOXO family isoforms.
Santos BF, Grenho I, Martel PJ, Ferreira BI, Link W. Santos BF, et al. Among authors: link w. Cell Death Dis. 2023 Oct 27;14(10):702. doi: 10.1038/s41419-023-06177-1. Cell Death Dis. 2023. PMID: 37891184 Free PMC article. Review.
166 results