Kwong PD - Search Results

1

A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.

Martinez DR, Schäfer A, Gobeil S, Li D, De la Cruz G, Parks R, Lu X, Barr M, Stalls V, Janowska K, Beaudoin E, Manne K, Mansouri K, Edwards RJ, Cronin K, Yount B, Anasti K, Montgomery SA, Tang J, Golding H, Shen S, Zhou T, Kwong PD, Graham BS, Mascola JR, Montefiori DC, Alam SM, Sempowski G, Sempowski GD, Khurana S, Wiehe K, Saunders KO, Acharya P, Haynes BF, Baric RS. Martinez DR, et al. Among authors: kwong pd. Sci Transl Med. 2022 Jan 26;14(629):eabj7125. doi: 10.1126/scitranslmed.abj7125. Epub 2022 Jan 26. Sci Transl Med. 2022. PMID: 34726473 Free PMC article.

2

Enhancing protein crystallization through precipitant synergy.

Majeed S, Ofek G, Belachew A, Huang CC, Zhou T, Kwong PD. Majeed S, et al. Among authors: kwong pd. Structure. 2003 Sep;11(9):1061-70. doi: 10.1016/s0969-2126(03)00185-0. Structure. 2003. PMID: 12962625 Free article.

3

Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope.

Ofek G, Tang M, Sambor A, Katinger H, Mascola JR, Wyatt R, Kwong PD. Ofek G, et al. Among authors: kwong pd. J Virol. 2004 Oct;78(19):10724-37. doi: 10.1128/JVI.78.19.10724-10737.2004. J Virol. 2004. PMID: 15367639 Free PMC article.

4

Interfacial metal and antibody recognition.

Zhou T, Hamer DH, Hendrickson WA, Sattentau QJ, Kwong PD. Zhou T, et al. Among authors: kwong pd. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14575-80. doi: 10.1073/pnas.0507267102. Epub 2005 Sep 29. Proc Natl Acad Sci U S A. 2005. PMID: 16195378 Free PMC article.

5

Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity.

Dey B, Pancera M, Svehla K, Shu Y, Xiang SH, Vainshtein J, Li Y, Sodroski J, Kwong PD, Mascola JR, Wyatt R. Dey B, et al. Among authors: kwong pd. J Virol. 2007 Jun;81(11):5579-93. doi: 10.1128/JVI.02500-06. Epub 2007 Mar 14. J Virol. 2007. PMID: 17360741 Free PMC article.

6

Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4.

Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD. Huang CC, et al. Among authors: kwong pd. Science. 2007 Sep 28;317(5846):1930-4. doi: 10.1126/science.1145373. Science. 2007. PMID: 17901336 Free PMC article.

7

Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry.

Lam SN, Acharya P, Wyatt R, Kwong PD, Bewley CA. Lam SN, et al. Among authors: kwong pd. Bioorg Med Chem. 2008 Dec 1;16(23):10113-20. doi: 10.1016/j.bmc.2008.10.005. Epub 2008 Oct 5. Bioorg Med Chem. 2008. PMID: 18952441 Free PMC article.

8

Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain.

Wu L, Zhou T, Yang ZY, Svehla K, O'Dell S, Louder MK, Xu L, Mascola JR, Burton DR, Hoxie JA, Doms RW, Kwong PD, Nabel GJ. Wu L, et al. Among authors: kwong pd. J Virol. 2009 May;83(10):5077-86. doi: 10.1128/JVI.02600-08. Epub 2009 Mar 4. J Virol. 2009. PMID: 19264769 Free PMC article.

9

Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site.

Dey B, Svehla K, Xu L, Wycuff D, Zhou T, Voss G, Phogat A, Chakrabarti BK, Li Y, Shaw G, Kwong PD, Nabel GJ, Mascola JR, Wyatt RT. Dey B, et al. Among authors: kwong pd. PLoS Pathog. 2009 May;5(5):e1000445. doi: 10.1371/journal.ppat.1000445. Epub 2009 May 29. PLoS Pathog. 2009. PMID: 19478876 Free PMC article.

10

Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachment.

Wu X, Zhou T, O'Dell S, Wyatt RT, Kwong PD, Mascola JR. Wu X, et al. Among authors: kwong pd. J Virol. 2009 Nov;83(21):10892-907. doi: 10.1128/JVI.01142-09. Epub 2009 Aug 19. J Virol. 2009. PMID: 19692465 Free PMC article.

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