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Inflammasome activation in infected macrophages drives COVID-19 pathology.
Sefik E, Qu R, Junqueira C, Kaffe E, Mirza H, Zhao J, Brewer JR, Han A, Steach HR, Israelow B, Blackburn HN, Velazquez SE, Chen YG, Halene S, Iwasaki A, Meffre E, Nussenzweig M, Lieberman J, Wilen CB, Kluger Y, Flavell RA. Sefik E, et al. Among authors: junqueira c. Nature. 2022 Jun;606(7914):585-593. doi: 10.1038/s41586-022-04802-1. Epub 2022 Apr 28. Nature. 2022. PMID: 35483404 Free PMC article.
Cytotoxic CD8+ T cells recognize and kill Plasmodium vivax-infected reticulocytes.
Junqueira C, Barbosa CRR, Costa PAC, Teixeira-Carvalho A, Castro G, Sen Santara S, Barbosa RP, Dotiwala F, Pereira DB, Antonelli LR, Lieberman J, Gazzinelli RT. Junqueira C, et al. Nat Med. 2018 Sep;24(9):1330-1336. doi: 10.1038/s41591-018-0117-4. Epub 2018 Jul 23. Nat Med. 2018. PMID: 30038217 Free PMC article.
Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
Zhang Z, Zhang Y, Xia S, Kong Q, Li S, Liu X, Junqueira C, Meza-Sosa KF, Mok TMY, Ansara J, Sengupta S, Yao Y, Wu H, Lieberman J. Zhang Z, et al. Among authors: junqueira c. Nature. 2020 Mar;579(7799):415-420. doi: 10.1038/s41586-020-2071-9. Epub 2020 Mar 11. Nature. 2020. PMID: 32188940 Free PMC article.
Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts.
Crespo ÂC, Mulik S, Dotiwala F, Ansara JA, Sen Santara S, Ingersoll K, Ovies C, Junqueira C, Tilburgs T, Strominger JL, Lieberman J. Crespo ÂC, et al. Among authors: junqueira c. Cell. 2020 Sep 3;182(5):1125-1139.e18. doi: 10.1016/j.cell.2020.07.019. Epub 2020 Aug 20. Cell. 2020. PMID: 32822574 Free PMC article.
SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release.
Junqueira C, Crespo Â, Ranjbar S, Lewandrowski M, Ingber J, de Lacerda LB, Parry B, Ravid S, Clark S, Ho F, Vora SM, Leger V, Beakes C, Margolin J, Russell N, Kays K, Gehrke L, Adhikari UD, Henderson L, Janssen E, Kwon D, Sander C, Abraham J, Filbin M, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Lieberman J. Junqueira C, et al. Res Sq [Preprint]. 2021 Aug 11:rs.3.rs-153628. doi: 10.21203/rs.3.rs-153628/v1. Res Sq. 2021. PMID: 34401873 Free PMC article. Updated. Preprint.
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Junqueira C, Crespo Â, Ranjbar S, de Lacerda LB, Lewandrowski M, Ingber J, Parry B, Ravid S, Clark S, Schrimpf MR, Ho F, Beakes C, Margolin J, Russell N, Kays K, Boucau J, Das Adhikari U, Vora SM, Leger V, Gehrke L, Henderson LA, Janssen E, Kwon D, Sander C, Abraham J, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Filbin MR, Lieberman J. Junqueira C, et al. Nature. 2022 Jun;606(7914):576-584. doi: 10.1038/s41586-022-04702-4. Epub 2022 Apr 6. Nature. 2022. PMID: 35385861 Free PMC article.
The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells.
Sen Santara S, Lee DJ, Crespo Â, Hu JJ, Walker C, Ma X, Zhang Y, Chowdhury S, Meza-Sosa KF, Lewandrowski M, Zhang H, Rowe M, McClelland A, Wu H, Junqueira C, Lieberman J. Sen Santara S, et al. Among authors: junqueira c. Nature. 2023 Apr;616(7956):348-356. doi: 10.1038/s41586-023-05912-0. Epub 2023 Apr 5. Nature. 2023. PMID: 37020026 Free PMC article.
76 results