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Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Bogeska R, Mikecin AM, Kaschutnig P, Fawaz M, Büchler-Schäff M, Le D, Ganuza M, Vollmer A, Paffenholz SV, Asada N, Rodriguez-Correa E, Frauhammer F, Buettner F, Ball M, Knoch J, Stäble S, Walter D, Petri A, Carreño-Gonzalez MJ, Wagner V, Brors B, Haas S, Lipka DB, Essers MAG, Weru V, Holland-Letz T, Mallm JP, Rippe K, Krämer S, Schlesner M, McKinney Freeman S, Florian MC, King KY, Frenette PS, Rieger MA, Milsom MD. Bogeska R, et al. Among authors: mckinney freeman s. Cell Stem Cell. 2022 Aug 4;29(8):1273-1284.e8. doi: 10.1016/j.stem.2022.06.012. Epub 2022 Jul 19. Cell Stem Cell. 2022. PMID: 35858618 Free PMC article.
Muscle-derived hematopoietic stem cells are hematopoietic in origin.
McKinney-Freeman SL, Jackson KA, Camargo FD, Ferrari G, Mavilio F, Goodell MA. McKinney-Freeman SL, et al. Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1341-6. doi: 10.1073/pnas.032438799. Proc Natl Acad Sci U S A. 2002. PMID: 11830662 Free PMC article.
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway.
Lengerke C, Schmitt S, Bowman TV, Jang IH, Maouche-Chretien L, McKinney-Freeman S, Davidson AJ, Hammerschmidt M, Rentzsch F, Green JB, Zon LI, Daley GQ. Lengerke C, et al. Among authors: mckinney freeman s. Cell Stem Cell. 2008 Jan 10;2(1):72-82. doi: 10.1016/j.stem.2007.10.022. Cell Stem Cell. 2008. PMID: 18371423 Free article.
The transcriptional landscape of hematopoietic stem cell ontogeny.
McKinney-Freeman S, Cahan P, Li H, Lacadie SA, Huang HT, Curran M, Loewer S, Naveiras O, Kathrein KL, Konantz M, Langdon EM, Lengerke C, Zon LI, Collins JJ, Daley GQ. McKinney-Freeman S, et al. Cell Stem Cell. 2012 Nov 2;11(5):701-14. doi: 10.1016/j.stem.2012.07.018. Cell Stem Cell. 2012. PMID: 23122293 Free PMC article.
Effect of developmental stage of HSC and recipient on transplant outcomes.
Arora N, Wenzel PL, McKinney-Freeman SL, Ross SJ, Kim PG, Chou SS, Yoshimoto M, Yoder MC, Daley GQ. Arora N, et al. Among authors: mckinney freeman sl. Dev Cell. 2014 Jun 9;29(5):621-628. doi: 10.1016/j.devcel.2014.04.013. Dev Cell. 2014. PMID: 24914562 Free PMC article.
Functional screen identifies regulators of murine hematopoietic stem cell repopulation.
Holmfeldt P, Ganuza M, Marathe H, He B, Hall T, Kang G, Moen J, Pardieck J, Saulsberry AC, Cico A, Gaut L, McGoldrick D, Finkelstein D, Tan K, McKinney-Freeman S. Holmfeldt P, et al. Among authors: mckinney freeman s. J Exp Med. 2016 Mar 7;213(3):433-49. doi: 10.1084/jem.20150806. Epub 2016 Feb 15. J Exp Med. 2016. PMID: 26880577 Free PMC article.
Hematopoietic stem cells under pressure.
Ganuza M, McKinney-Freeman S. Ganuza M, et al. Among authors: mckinney freeman s. Curr Opin Hematol. 2017 Jul;24(4):314-321. doi: 10.1097/MOH.0000000000000347. Curr Opin Hematol. 2017. PMID: 28375987 Free PMC article. Review.
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