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Histone H4K16ac Binding Function of the Triple PHD Finger Cassette of MLL4.
Kumar Sinha V, Zhang Y, Xu L, Chen YW, Picaud S, Zandian M, Biswas S, Filippakopoulos P, Wang SP, Shi X, Kutateladze TG. Kumar Sinha V, et al. Among authors: filippakopoulos p. J Mol Biol. 2024 Apr 1;436(7):168212. doi: 10.1016/j.jmb.2023.168212. Epub 2023 Jul 20. J Mol Biol. 2024. PMID: 37481158
Small-molecule inhibitors of the c-Fes protein-tyrosine kinase.
Hellwig S, Miduturu CV, Kanda S, Zhang J, Filippakopoulos P, Salah E, Deng X, Choi HG, Zhou W, Hur W, Knapp S, Gray NS, Smithgall TE. Hellwig S, et al. Among authors: filippakopoulos p. Chem Biol. 2012 Apr 20;19(4):529-40. doi: 10.1016/j.chembiol.2012.01.020. Chem Biol. 2012. PMID: 22520759 Free PMC article.
Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Debdab M, Carreaux F, Renault S, Soundararajan M, Fedorov O, Filippakopoulos P, Lozach O, Babault L, Tahtouh T, Baratte B, Ogawa Y, Hagiwara M, Eisenreich A, Rauch U, Knapp S, Meijer L, Bazureau JP. Debdab M, et al. Among authors: filippakopoulos p. J Med Chem. 2011 Jun 23;54(12):4172-86. doi: 10.1021/jm200274d. Epub 2011 May 26. J Med Chem. 2011. PMID: 21615147
Similar biological activities of two isostructural ruthenium and osmium complexes.
Maksimoska J, Williams DS, Atilla-Gokcumen GE, Smalley KS, Carroll PJ, Webster RD, Filippakopoulos P, Knapp S, Herlyn M, Meggers E. Maksimoska J, et al. Among authors: filippakopoulos p. Chemistry. 2008;14(16):4816-22. doi: 10.1002/chem.200800294. Chemistry. 2008. PMID: 18425743 Free PMC article.
Structural and functional characterization of the human protein kinase ASK1.
Bunkoczi G, Salah E, Filippakopoulos P, Fedorov O, Müller S, Sobott F, Parker SA, Zhang H, Min W, Turk BE, Knapp S. Bunkoczi G, et al. Among authors: filippakopoulos p. Structure. 2007 Oct;15(10):1215-26. doi: 10.1016/j.str.2007.08.011. Structure. 2007. PMID: 17937911 Free PMC article.
Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases.
Myrianthopoulos V, Kritsanida M, Gaboriaud-Kolar N, Magiatis P, Ferandin Y, Durieu E, Lozach O, Cappel D, Soundararajan M, Filippakopoulos P, Sherman W, Knapp S, Meijer L, Mikros E, Skaltsounis AL. Myrianthopoulos V, et al. Among authors: filippakopoulos p. ACS Med Chem Lett. 2013 Jan 10;4(1):22-26. doi: 10.1021/ml300207a. Epub 2012 Nov 1. ACS Med Chem Lett. 2013. PMID: 23336033 Free PMC article.
96 results