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The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated antitumor immunity.
Lim J, Rodriguez R, Williams K, Silva J, Gutierrez AG, Tyler P, Baharom F, Sun T, Lin E, Martin S, Kayser BD, Johnston RJ, Mellman I, Delamarre L, West NR, Müller S, Qu Y, Heger K. Lim J, et al. Among authors: williams k. Cancer Immunol Res. 2024 Mar 18. doi: 10.1158/2326-6066.CIR-23-1078. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38489753
Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors.
Castiglioni A, Yang Y, Williams K, Gogineni A, Lane RS, Wang AW, Shyer JA, Zhang Z, Mittman S, Gutierrez A, Astarita JL, Thai M, Hung J, Yang YA, Pourmohamad T, Himmels P, De Simone M, Elstrott J, Capietto AH, Cubas R, Modrusan Z, Sandoval W, Ziai J, Gould SE, Fu W, Wang Y, Koerber JT, Sanjabi S, Mellman I, Turley SJ, Müller S. Castiglioni A, et al. Among authors: williams k. Nat Commun. 2023 Aug 5;14(1):4703. doi: 10.1038/s41467-023-40398-4. Nat Commun. 2023. PMID: 37543621 Free PMC article.
Durable lymph-node expansion is associated with the efficacy of therapeutic vaccination.
Najibi AJ, Lane RS, Sobral MC, Bovone G, Kang S, Freedman BR, Gutierrez Estupinan J, Elosegui-Artola A, Tringides CM, Dellacherie MO, Williams K, Ijaz H, Müller S, Turley SJ, Mooney DJ. Najibi AJ, et al. Among authors: williams k. Nat Biomed Eng. 2024 May 6. doi: 10.1038/s41551-024-01209-3. Online ahead of print. Nat Biomed Eng. 2024. PMID: 38710838
Sex-based differences in dermatomyositis: a retrospective study.
Lin RR, Warp PV, Williams KN, Elman SA, Maderal AD. Lin RR, et al. Among authors: williams kn. Arch Dermatol Res. 2024 May 31;316(6):297. doi: 10.1007/s00403-024-03104-y. Arch Dermatol Res. 2024. PMID: 38819470 No abstract available.
7,721 results