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Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma.
Colombo AR, Hav M, Singh M, Xu A, Gamboa A, Lemos T, Gerdtsson E, Chen D, Houldsworth J, Shaknovich R, Aoki T, Chong L, Takata K, Chavez EA, Steidl C, Hicks J, Kuhn P, Siddiqi I, Merchant A. Colombo AR, et al. Among authors: merchant a. Blood Adv. 2022 Aug 23;6(16):4675-4690. doi: 10.1182/bloodadvances.2022007493. Blood Adv. 2022. PMID: 35675517 Free PMC article.
A Paratope-Enhanced Method to Determine Breadth and Depth TCR Clonal Metrics of the Private Human T-Cell Vaccine Response after SARS-CoV-2 Vaccination.
Li D, Pavlovitch-Bedzyk AJ, Ebinger JE, Khan A, Hamideh M, Merchant A, Figueiredo JC, Cheng S, Davis MM, McGovern DPB, Melmed GY, Xu AM, Braun J. Li D, et al. Among authors: merchant a. Int J Mol Sci. 2023 Sep 18;24(18):14223. doi: 10.3390/ijms241814223. Int J Mol Sci. 2023. PMID: 37762524 Free PMC article.
Spatially Resolved Tumor Microenvironment Predicts Treatment Outcomes in Relapsed/Refractory Hodgkin Lymphoma.
Aoki T, Jiang A, Xu A, Yin Y, Gamboa A, Milne K, Takata K, Miyata-Takata T, Chung S, Rai S, Wu S, Warren M, Strong C, Goodyear T, Morris K, Chong LC, Hav M, Colombo AR, Telenius A, Boyle M, Ben-Neriah S, Power M, Gerrie AS, Weng AP, Karsan A, Roth A, Farinha P, Scott DW, Savage KJ, Nelson BH, Merchant A, Steidl C. Aoki T, et al. Among authors: merchant a. J Clin Oncol. 2024 Mar 20;42(9):1077-1087. doi: 10.1200/JCO.23.01115. Epub 2023 Dec 19. J Clin Oncol. 2024. PMID: 38113419 Free PMC article.
Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial.
Nawrocki ST, Olea J, Villa Celi C, Dadrastoussi H, Wu K, Tsao-Wei D, Colombo A, Coffey M, Fernandez Hernandez E, Chen X, Nuovo GJ, Carew JS, Mohrbacher AF, Fields P, Kuhn P, Siddiqi I, Merchant A, Kelly KR. Nawrocki ST, et al. Among authors: merchant a. Clin Cancer Res. 2023 Dec 15;29(24):5087-5103. doi: 10.1158/1078-0432.CCR-23-0229. Clin Cancer Res. 2023. PMID: 37812476 Free PMC article. Clinical Trial.
Low booster uptake in cancer patients despite health benefits.
Figueiredo JC, Levy J, Choi SY, Xu AM, Merin NM, Hamid O, Lemos T, Nguyen N, Nadri M, Gonzalez A, Mahov S, Darrah JM, Gong J, Paquette RL, Mita AC, Vescio RA, Salvy SJ, Mehmi I, Hendifar AE, Natale R, Tourtellotte WG, Krishnan Ramanujan V, Huynh CA, Sobhani K, Reckamp KL, Merchant AA. Figueiredo JC, et al. Among authors: merchant aa. medRxiv [Preprint]. 2023 Oct 26:2023.10.25.23297483. doi: 10.1101/2023.10.25.23297483. medRxiv. 2023. PMID: 37961284 Free PMC article. Preprint.
EPHB4 is a therapeutic target in AML and promotes leukemia cell survival via AKT.
Merchant AA, Jorapur A, McManus A, Liu R, Krasnoperov V, Chaudhry P, Singh M, Harton L, Agajanian M, Kim M, Triche TJ Jr, Druker BJ, Tyner JW, Gill PS. Merchant AA, et al. Blood Adv. 2017 Aug 28;1(20):1635-1644. doi: 10.1182/bloodadvances.2017005694. eCollection 2017 Sep 12. Blood Adv. 2017. PMID: 29296810 Free PMC article.
Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial.
Heuser M, Smith BD, Fiedler W, Sekeres MA, Montesinos P, Leber B, Merchant A, Papayannidis C, Pérez-Simón JA, Hoang CJ, O'Brien T, Ma WW, Zeremski M, O'Connell A, Chan G, Cortes JE. Heuser M, et al. Among authors: merchant a. Ann Hematol. 2021 May;100(5):1181-1194. doi: 10.1007/s00277-021-04465-4. Epub 2021 Mar 19. Ann Hematol. 2021. PMID: 33740113 Free PMC article. Clinical Trial.
Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses.
Contreras-Trujillo H, Eerdeng J, Akre S, Jiang D, Contreras J, Gala B, Vergel-Rodriguez MC, Lee Y, Jorapur A, Andreasian A, Harton L, Bramlett CS, Nogalska A, Xiao G, Lee JW, Chan LN, Müschen M, Merchant AA, Lu R. Contreras-Trujillo H, et al. Among authors: merchant aa. Nat Commun. 2021 Nov 11;12(1):6522. doi: 10.1038/s41467-021-26771-1. Nat Commun. 2021. PMID: 34764253 Free PMC article.
687 results