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Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.
Meyers RM, Bryan JG, McFarland JM, Weir BA, Sizemore AE, Xu H, Dharia NV, Montgomery PG, Cowley GS, Pantel S, Goodale A, Lee Y, Ali LD, Jiang G, Lubonja R, Harrington WF, Strickland M, Wu T, Hawes DC, Zhivich VA, Wyatt MR, Kalani Z, Chang JJ, Okamoto M, Stegmaier K, Golub TR, Boehm JS, Vazquez F, Root DE, Hahn WC, Tsherniak A. Meyers RM, et al. Among authors: hahn wc. Nat Genet. 2017 Dec;49(12):1779-1784. doi: 10.1038/ng.3984. Epub 2017 Oct 30. Nat Genet. 2017. PMID: 29083409 Free PMC article.
Understanding transformation: progress and gaps.
Boehm JS, Hahn WC. Boehm JS, et al. Among authors: hahn wc. Curr Opin Genet Dev. 2005 Feb;15(1):13-7. doi: 10.1016/j.gde.2004.11.003. Curr Opin Genet Dev. 2005. PMID: 15661528 Review.
Cancer genetics: Finding the right mix.
Boehm JS, Hahn WC. Boehm JS, et al. Among authors: hahn wc. Eur J Hum Genet. 2005 Oct;13(10):1099-100. doi: 10.1038/sj.ejhg.5201477. Eur J Hum Genet. 2005. PMID: 16077731 No abstract available.
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen.
Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE. Moffat J, et al. Among authors: hahn wc. Cell. 2006 Mar 24;124(6):1283-98. doi: 10.1016/j.cell.2006.01.040. Cell. 2006. PMID: 16564017 Free article.
Minimizing the risk of reporting false positives in large-scale RNAi screens.
Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prévôt B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R. Echeverri CJ, et al. Among authors: hahn wc. Nat Methods. 2006 Oct;3(10):777-9. doi: 10.1038/nmeth1006-777. Nat Methods. 2006. PMID: 16990807
373 results