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Page 1
Defining a Cancer Dependency Map.
Tsherniak A, Vazquez F, Montgomery PG, Weir BA, Kryukov G, Cowley GS, Gill S, Harrington WF, Pantel S, Krill-Burger JM, Meyers RM, Ali L, Goodale A, Lee Y, Jiang G, Hsiao J, Gerath WFJ, Howell S, Merkel E, Ghandi M, Garraway LA, Root DE, Golub TR, Boehm JS, Hahn WC. Tsherniak A, et al. Among authors: howell s. Cell. 2017 Jul 27;170(3):564-576.e16. doi: 10.1016/j.cell.2017.06.010. Cell. 2017. PMID: 28753430 Free PMC article.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Cowley GS, Weir BA, Vazquez F, Tamayo P, Scott JA, Rusin S, East-Seletsky A, Ali LD, Gerath WF, Pantel SE, Lizotte PH, Jiang G, Hsiao J, Tsherniak A, Dwinell E, Aoyama S, Okamoto M, Harrington W, Gelfand E, Green TM, Tomko MJ, Gopal S, Wong TC, Li H, Howell S, Stransky N, Liefeld T, Jang D, Bistline J, Hill Meyers B, Armstrong SA, Anderson KC, Stegmaier K, Reich M, Pellman D, Boehm JS, Mesirov JP, Golub TR, Root DE, Hahn WC. Cowley GS, et al. Among authors: howell s. Sci Data. 2014 Sep 30;1:140035. doi: 10.1038/sdata.2014.35. eCollection 2014. Sci Data. 2014. PMID: 25984343 Free PMC article.
Integrated genetic and pharmacologic interrogation of rare cancers.
Hong AL, Tseng YY, Cowley GS, Jonas O, Cheah JH, Kynnap BD, Doshi MB, Oh C, Meyer SC, Church AJ, Gill S, Bielski CM, Keskula P, Imamovic A, Howell S, Kryukov GV, Clemons PA, Tsherniak A, Vazquez F, Crompton BD, Shamji AF, Rodriguez-Galindo C, Janeway KA, Roberts CW, Stegmaier K, van Hummelen P, Cima MJ, Langer RS, Garraway LA, Schreiber SL, Root DE, Hahn WC, Boehm JS. Hong AL, et al. Among authors: howell s. Nat Commun. 2016 Jun 22;7:11987. doi: 10.1038/ncomms11987. Nat Commun. 2016. PMID: 27329820 Free PMC article.
A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines.
Gönen M, Weir BA, Cowley GS, Vazquez F, Guan Y, Jaiswal A, Karasuyama M, Uzunangelov V, Wang T, Tsherniak A, Howell S, Marbach D, Hoff B, Norman TC, Airola A, Bivol A, Bunte K, Carlin D, Chopra S, Deran A, Ellrott K, Gopalacharyulu P, Graim K, Kaski S, Khan SA, Newton Y, Ng S, Pahikkala T, Paull E, Sokolov A, Tang H, Tang J, Wennerberg K, Xie Y, Zhan X, Zhu F; Broad-DREAM Community; Aittokallio T, Mamitsuka H, Stuart JM, Boehm JS, Root DE, Xiao G, Stolovitzky G, Hahn WC, Margolin AA. Gönen M, et al. Among authors: howell s. Cell Syst. 2017 Nov 22;5(5):485-497.e3. doi: 10.1016/j.cels.2017.09.004. Epub 2017 Oct 4. Cell Syst. 2017. PMID: 28988802 Free PMC article.
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2.
Bashore FM, Min SM, Chen X, Howell S, Rinderle CH, Morel G, Silvaroli JA, Wells CI, Bunnell BA, Drewry DH, Pabla NS, Ultanir SK, Bullock AN, Axtman AD. Bashore FM, et al. Among authors: howell s. bioRxiv [Preprint]. 2024 May 14:2024.05.12.593776. doi: 10.1101/2024.05.12.593776. bioRxiv. 2024. PMID: 38798634 Free PMC article. Preprint.
Association between self-reported functional capacity measures and postoperative myocardial injury in patients undergoing noncardiac surgeries.
Polok K, Buse GL, Mauermann E, Ionescu D, Fronczek J, De Hert S, Filipovic M, Beck Schimmer B, van Waes J, Gillmann HJ, Schultze C, Kotfis K, Howell SJ, Studzińska D, Espeter F, Jung-König M, Larmann J, Szczeklik W, Metrepair Investigators T. Polok K, et al. Among authors: howell sj. Kardiol Pol. 2024 May 20. doi: 10.33963/v.phj.100567. Online ahead of print. Kardiol Pol. 2024. PMID: 38767162 Free article. No abstract available.
Engaging Stakeholders to Develop a Roadmap for Dry Eye and MGD PCORI-Funded Research.
Warren NA, Maskin SL, Gurupur V, Rector DA, Adelman D, Howell S, McAree J, Dibble R, Carlisano C, Maconi DP, Schrotenboer D, Jaimes M, Marte N, Carlisano T, Toland C, Chung J, Cremers SL, Corbin GS. Warren NA, et al. Among authors: howell s. Patient Relat Outcome Meas. 2024 May 12;15:143-186. doi: 10.2147/PROM.S438290. eCollection 2024. Patient Relat Outcome Meas. 2024. PMID: 38764936 Free PMC article.
2,031 results