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Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis.
Jiang R, Hoehn KB, Lee CS, Pham MC, Homer RJ, Detterbeck FC, Aban I, Jacobson L, Vincent A, Nowak RJ, Kaminski HJ, Kleinstein SH, O'Connor KC. Jiang R, et al. Among authors: kleinstein sh. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30649-30660. doi: 10.1073/pnas.2007206117. Epub 2020 Nov 16. Proc Natl Acad Sci U S A. 2020. PMID: 33199596 Free PMC article.
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data.
Yaari G, Vander Heiden JA, Uduman M, Gadala-Maria D, Gupta N, Stern JN, O'Connor KC, Hafler DA, Laserson U, Vigneault F, Kleinstein SH. Yaari G, et al. Among authors: kleinstein sh. Front Immunol. 2013 Nov 15;4:358. doi: 10.3389/fimmu.2013.00358. eCollection 2013. Front Immunol. 2013. PMID: 24298272 Free PMC article.
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes.
Stern JN, Yaari G, Vander Heiden JA, Church G, Donahue WF, Hintzen RQ, Huttner AJ, Laman JD, Nagra RM, Nylander A, Pitt D, Ramanan S, Siddiqui BA, Vigneault F, Kleinstein SH, Hafler DA, O'Connor KC. Stern JN, et al. Among authors: kleinstein sh. Sci Transl Med. 2014 Aug 6;6(248):248ra107. doi: 10.1126/scitranslmed.3008879. Sci Transl Med. 2014. PMID: 25100741 Free PMC article.
Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing.
Vander Heiden JA, Stathopoulos P, Zhou JQ, Chen L, Gilbert TJ, Bolen CR, Barohn RJ, Dimachkie MM, Ciafaloni E, Broering TJ, Vigneault F, Nowak RJ, Kleinstein SH, O'Connor KC. Vander Heiden JA, et al. Among authors: kleinstein sh. J Immunol. 2017 Feb 15;198(4):1460-1473. doi: 10.4049/jimmunol.1601415. Epub 2017 Jan 13. J Immunol. 2017. PMID: 28087666 Free PMC article.
184 results