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βA3/A1-crystallin and persistent fetal vasculature (PFV) disease of the eye.
Zigler JS Jr, Valapala M, Shang P, Hose S, Goldberg MF, Sinha D. Zigler JS Jr, et al. Among authors: valapala m. Biochim Biophys Acta. 2016 Jan;1860(1 Pt B):287-98. doi: 10.1016/j.bbagen.2015.05.017. Epub 2015 May 31. Biochim Biophys Acta. 2016. PMID: 26022148 Free PMC article. Review.
Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.
Valapala M, Wilson C, Hose S, Bhutto IA, Grebe R, Dong A, Greenbaum S, Gu L, Sengupta S, Cano M, Hackett S, Xu G, Lutty GA, Dong L, Sergeev Y, Handa JT, Campochiaro P, Wawrousek E, Zigler JS Jr, Sinha D. Valapala M, et al. Autophagy. 2014 Mar;10(3):480-96. doi: 10.4161/auto.27292. Epub 2014 Jan 23. Autophagy. 2014. PMID: 24468901 Free PMC article.
Lysosomes: Regulators of autophagy in the retinal pigmented epithelium.
Sinha D, Valapala M, Shang P, Hose S, Grebe R, Lutty GA, Zigler JS Jr, Kaarniranta K, Handa JT. Sinha D, et al. Among authors: valapala m. Exp Eye Res. 2016 Mar;144:46-53. doi: 10.1016/j.exer.2015.08.018. Epub 2015 Aug 28. Exp Eye Res. 2016. PMID: 26321509 Free PMC article. Review.
The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling.
Shang P, Valapala M, Grebe R, Hose S, Ghosh S, Bhutto IA, Handa JT, Lutty GA, Lu L, Wan J, Qian J, Sergeev Y, Puertollano R, Zigler JS Jr, Xu GT, Sinha D. Shang P, et al. Among authors: valapala m. Aging Cell. 2017 Apr;16(2):349-359. doi: 10.1111/acel.12561. Epub 2017 Jan 13. Aging Cell. 2017. PMID: 28083894 Free PMC article.
The role of lipocalin-2 in age-related macular degeneration (AMD).
Ghosh S, Stepicheva N, Yazdankhah M, Shang P, Watson AM, Hose S, Liu H, Weiss J, Zigler JS Jr, Valapala M, Watkins SC, Sinha D. Ghosh S, et al. Among authors: valapala m. Cell Mol Life Sci. 2020 Mar;77(5):835-851. doi: 10.1007/s00018-019-03423-8. Epub 2020 Jan 4. Cell Mol Life Sci. 2020. PMID: 31901947 Free PMC article. Review.
22 results