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Inhibition of neuraminidase-1 sialidase activity by interfering peptides impairs insulin receptor activity in vitro and glucose homeostasis in vivo.
Toussaint K, Appert-Collin A, Vanalderwiert L, Bour C, Terryn C, Spenlé C, Van Der Heyden M, Roumieux M, Maurice P, Romier-Crouzet B, Sartelet H, Duca L, Blaise S, Bennasroune A. Toussaint K, et al. Among authors: spenle c. J Biol Chem. 2024 Apr 23;300(6):107316. doi: 10.1016/j.jbc.2024.107316. Online ahead of print. J Biol Chem. 2024. PMID: 38663826 Free article.
Impact of Tenascin-C on Radiotherapy in a Novel Syngeneic Oral Squamous Cell Carcinoma Model With Spontaneous Dissemination to the Lymph Nodes.
Spenlé C, Loustau T, Burckel H, Riegel G, Abou Faycal C, Li C, Yilmaz A, Petti L, Steinbach F, Ahowesso C, Jost C, Paul N, Carapito R, Noël G, Anjuère F, Salomé N, Orend G. Spenlé C, et al. Front Immunol. 2021 Jul 5;12:636108. doi: 10.3389/fimmu.2021.636108. eCollection 2021. Front Immunol. 2021. PMID: 34290694 Free PMC article.
Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma.
Spenlé C, Loustau T, Murdamoothoo D, Erne W, Beghelli-de la Forest Divonne S, Veber R, Petti L, Bourdely P, Mörgelin M, Brauchle EM, Cremel G, Randrianarisoa V, Camara A, Rekima S, Schaub S, Nouhen K, Imhof T, Hansen U, Paul N, Carapito R, Pythoud N, Hirschler A, Carapito C, Dumortier H, Mueller CG, Koch M, Schenke-Layland K, Kon S, Sudaka A, Anjuère F, Van Obberghen-Schilling E, Orend G. Spenlé C, et al. Cancer Immunol Res. 2020 Sep;8(9):1122-1138. doi: 10.1158/2326-6066.CIR-20-0074. Epub 2020 Jul 14. Cancer Immunol Res. 2020. PMID: 32665262 Free article.
Disruption of Sema3A/Plexin-A1 inhibitory signalling in oligodendrocytes as a therapeutic strategy to promote remyelination.
Binamé F, Pham-Van LD, Spenlé C, Jolivel V, Birmpili D, Meyer LA, Jacob L, Meyer L, Mensah-Nyagan AG, Po C, Van der Heyden M, Roussel G, Bagnard D. Binamé F, et al. Among authors: spenle c. EMBO Mol Med. 2019 Nov 7;11(11):e10378. doi: 10.15252/emmm.201910378. Epub 2019 Sep 30. EMBO Mol Med. 2019. PMID: 31566924 Free PMC article.
Tenascin-C increases lung metastasis by impacting blood vessel invasions.
Sun Z, Velázquez-Quesada I, Murdamoothoo D, Ahowesso C, Yilmaz A, Spenlé C, Averous G, Erne W, Oberndorfer F, Oszwald A, Kain R, Bourdon C, Mangin P, Deligne C, Midwood K, Abou-Faycal C, Lefebvre O, Klein A, van der Heyden M, Chenard MP, Christofori G, Mathelin C, Loustau T, Hussenet T, Orend G. Sun Z, et al. Among authors: spenle c. Matrix Biol. 2019 Oct;83:26-47. doi: 10.1016/j.matbio.2019.07.001. Epub 2019 Jul 6. Matrix Biol. 2019. PMID: 31288084 Free article.
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