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APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease.
Fortea J, Pegueroles J, Alcolea D, Belbin O, Dols-Icardo O, Vaqué-Alcázar L, Videla L, Gispert JD, Suárez-Calvet M, Johnson SC, Sperling R, Bejanin A, Lleó A, Montal V. Fortea J, et al. Among authors: dols icardo o. Nat Med. 2024 May;30(5):1284-1291. doi: 10.1038/s41591-024-02931-w. Epub 2024 May 6. Nat Med. 2024. PMID: 38710950
Network Tau spreading is vulnerable to the expression gradients of APOE and glutamatergic-related genes.
Montal V, Diez I, Kim CM, Orwig W, Bueichekú E, Gutiérrez-Zúñiga R, Bejanin A, Pegueroles J, Dols-Icardo O, Vannini P, El-Fakhri G, Johnson KA, Sperling RA, Fortea J, Sepulcre J. Montal V, et al. Sci Transl Med. 2022 Jul 27;14(655):eabn7273. doi: 10.1126/scitranslmed.abn7273. Epub 2022 Jul 27. Sci Transl Med. 2022. PMID: 35895837 Free PMC article.
Amyloid precursor protein 𝛽CTF accumulates in synapses in sporadic and genetic forms of Alzheimer's disease.
Ferrer-Raventós P, Puertollano-Martín D, Querol-Vilaseca M, Sánchez-Aced É, Valle-Tamayo N, Cervantes-Gonzalez A, Nuñez-Llaves R, Pegueroles J, Dols-Icardo O, Iulita MF, Aldecoa I, Molina-Porcel L, Sánchez-Valle R, Fortea J, Belbin O, Sirisi S, Lleó A. Ferrer-Raventós P, et al. Among authors: dols icardo o. Neuropathol Appl Neurobiol. 2023 Feb;49(1):e12879. doi: 10.1111/nan.12879. Neuropathol Appl Neurobiol. 2023. PMID: 36702749
Effect of REST on brain metabolism in the Alzheimer disease continuum.
Dols-Icardo O, Vilaplana E, Sampedro F, Alcolea D, Belbin O, Camacho V, Blesa R, Lleó A, Clarimón J, Fortea J; Alzheimer's Disease Neuroimaging Initiative. Dols-Icardo O, et al. Ann Neurol. 2015 Oct;78(4):661-2. doi: 10.1002/ana.24484. Epub 2015 Aug 25. Ann Neurol. 2015. PMID: 26179831 No abstract available.
MAPT H1 Haplotype is Associated with Late-Onset Alzheimer's Disease Risk in APOEɛ4 Noncarriers: Results from the Dementia Genetics Spanish Consortium.
Pastor P, Moreno F, Clarimón J, Ruiz A, Combarros O, Calero M, López de Munain A, Bullido MJ, de Pancorbo MM, Carro E, Antonell A, Coto E, Ortega-Cubero S, Hernandez I, Tárraga L, Boada M, Lleó A, Dols-Icardo O, Kulisevsky J, Vázquez-Higuera JL, Infante J, Rábano A, Fernández-Blázquez MÁ, Valentí M, Indakoetxea B, Barandiarán M, Gorostidi A, Frank-García A, Sastre I, Lorenzo E, Pastor MA, Elcoroaristizabal X, Lennarz M, Maier W, Rámirez A, Serrano-Ríos M, Lee SE, Sánchez-Juan P; Dementia Genetic Spanish Consortium (DEGESCO). Pastor P, et al. J Alzheimers Dis. 2016;49(2):343-52. doi: 10.3233/JAD-150555. J Alzheimers Dis. 2016. PMID: 26444794 Free article.
CSF sAPPβ, YKL-40, and NfL along the ALS-FTD spectrum.
Illán-Gala I, Alcolea D, Montal V, Dols-Icardo O, Muñoz L, de Luna N, Turón-Sans J, Cortés-Vicente E, Sánchez-Saudinós MB, Subirana A, Sala I, Blesa R, Clarimón J, Fortea J, Rojas-García R, Lleó A. Illán-Gala I, et al. Neurology. 2018 Oct 23;91(17):e1619-e1628. doi: 10.1212/WNL.0000000000006383. Epub 2018 Oct 5. Neurology. 2018. PMID: 30291183
The Sant Pau Initiative on Neurodegeneration (SPIN) cohort: A data set for biomarker discovery and validation in neurodegenerative disorders.
Alcolea D, Clarimón J, Carmona-Iragui M, Illán-Gala I, Morenas-Rodríguez E, Barroeta I, Ribosa-Nogué R, Sala I, Sánchez-Saudinós MB, Videla L, Subirana A, Benejam B, Valldeneu S, Fernández S, Estellés T, Altuna M, Santos-Santos M, García-Losada L, Bejanin A, Pegueroles J, Montal V, Vilaplana E, Belbin O, Dols-Icardo O, Sirisi S, Querol-Vilaseca M, Cervera-Carles L, Muñoz L, Núñez R, Torres S, Camacho MV, Carrió I, Giménez S, Delaby C, Rojas-Garcia R, Turon-Sans J, Pagonabarraga J, Jiménez A, Blesa R, Fortea J, Lleó A. Alcolea D, et al. Alzheimers Dement (N Y). 2019 Oct 14;5:597-609. doi: 10.1016/j.trci.2019.09.005. eCollection 2019. Alzheimers Dement (N Y). 2019. PMID: 31650016 Free PMC article.
Neuropathology of a patient with Alzheimer disease treated with low doses of verubecestat.
Querol-Vilaseca M, Sirisi S, Molina-Porcel L, Molina B, Pegueroles J, Ferrer-Raventós P, Nuñez-Llaves R, Dols-Icardo O, Balasa M, Iulita MF, Blesa R, Belbin O, Clarimon J, Fortea J, Gelpi E, Sánchez-Valle R, Lleó A. Querol-Vilaseca M, et al. Neuropathol Appl Neurobiol. 2022 Apr;48(3):e12781. doi: 10.1111/nan.12781. Epub 2021 Dec 7. Neuropathol Appl Neurobiol. 2022. PMID: 34825396
76 results