[Recurrent hepatitis in oral anticoagulation: coumarin-induced hepatitis]

Abstract

Coumarin hepatotoxicity resulting in a cholestatic or cytolytic hepatitis is a rare side effect in oral anticoagulant therapy, but has to be considered in any patient receiving coumarin treatment if hepatitis is diagnosed. Substitution with an other coumarin derivative is sometimes feasable, although cross-reactions between coumarin derivatives have been observed.