Two forms of reactive arthritis?

Ann Rheum Dis. 1999 Dec;58(12):737-41. doi: 10.1136/ard.58.12.737.

Abstract

Inflammatory arthritides developing after a distant infection have so far been called reactive or postinfectious, quite often depending on the microbial trigger and/or HLA-B27 status of the patient. For clarity, it is proposed that they all should be called reactive arthritis, which, according to the trigger, occurs as an HLA-B27 associated or non-associated form. In addition to the causative agents and HLA-B27, these two categories are also distinguished by other characteristics. Most important, HLA-B27 associated arthritis may occur identical to the Reiter's syndrome with accompanying ureteritis and/or conjunctivitis, whereas in the B27 non-associated form this has not been clearly described. Likewise, only the B27 associated form belongs to the group of spondyloarthropathies.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Arthritis, Reactive / classification*
  • Arthritis, Reactive / immunology
  • Arthritis, Reactive / microbiology
  • Bacterial Infections / immunology
  • HLA-B27 Antigen / analysis
  • Humans

Substances

  • HLA-B27 Antigen