Increased coverage of protein families with the blocks database servers

J G Henikoff; E A Greene; S Pietrokovski; S Henikoff

doi:10.1093/nar/28.1.228

Increased coverage of protein families with the blocks database servers

Nucleic Acids Res. 2000 Jan 1;28(1):228-30. doi: 10.1093/nar/28.1.228.

Authors

J G Henikoff¹, E A Greene, S Pietrokovski, S Henikoff

Affiliation

¹ Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109-1024, USA.

Abstract

The Blocks Database WWW (http://blocks.fhcrc.org ) and Email (blocks@blocks.fhcrc.org ) servers provide tools to search DNA and protein queries against the Blocks+ Database of multiple alignments, which represent conserved protein regions. Blocks+ nearly doubles the number of protein families included in the database by adding families from the Pfam-A, ProDom and Domo databases to those from PROSITE and PRINTS. Other new features include improved Block Searcher statistics, searching with NCBI's IMPALA program and 3D display of blocks on PDB structures.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Amino Acid Sequence
Databases, Factual*
Information Storage and Retrieval
Internet
Molecular Sequence Data
Proteins / chemistry*
Sequence Homology, Amino Acid

Substances

Proteins

Grants and funding

GM29009/GM/NIGMS NIH HHS/United States