Lipoproteins take their toll on the host

Curr Biol. 1999 Dec 2;9(23):R879-82. doi: 10.1016/s0960-9822(00)80073-1.

Abstract

A family of mammalian Toll-like receptors (TLRs) has a critical role in the recognition of microbial infection. Recent evidence suggests that bacterial lipoproteins - major components of bacterial cell walls - are recognized by a member of the human TLR family.

MeSH terms

  • Animals
  • Antigen Presentation*
  • Antigen-Presenting Cells / metabolism
  • Bacterial Infections / immunology*
  • Drosophila Proteins*
  • Humans
  • Immunity, Innate / physiology*
  • Lipoproteins / immunology*
  • Membrane Glycoproteins / immunology*
  • Membrane Glycoproteins / metabolism
  • Receptors, Cell Surface / immunology*
  • Receptors, Cell Surface / metabolism
  • Toll-Like Receptors

Substances

  • Drosophila Proteins
  • Lipoproteins
  • Membrane Glycoproteins
  • Receptors, Cell Surface
  • Toll-Like Receptors