An immunologically active arabinogalactan from Tinospora cordifolia

Phytochemistry. 1999 Nov;52(6):1089-93. doi: 10.1016/s0031-9422(99)00386-6.

Abstract

An arabinogalactan of mean M(r) 2.2 x 10(6) has been isolated from the dried stems of Tinospora cordifolia and examined by methylation analysis, partial hydrolysis and carboxyl reduction. Purified polysaccharide showed polyclonal mitogenic activity against B-cells, their proliferation did not require macrophages.

MeSH terms

  • Adjuvants, Immunologic / analysis
  • Adjuvants, Immunologic / isolation & purification*
  • Adjuvants, Immunologic / pharmacology*
  • Animals
  • Chromatography, Gel
  • Galactans / analysis
  • Galactans / isolation & purification*
  • Galactans / pharmacology*
  • Hydrolysis
  • Medicine, Ayurvedic
  • Methylation
  • Mice
  • Mitogens / analysis
  • Mitogens / isolation & purification
  • Mitogens / pharmacology
  • Plant Extracts / analysis
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Plants, Medicinal / chemistry*
  • Polysaccharides / analysis
  • Polysaccharides / isolation & purification
  • Polysaccharides / pharmacology

Substances

  • Adjuvants, Immunologic
  • Galactans
  • Mitogens
  • Plant Extracts
  • Polysaccharides
  • arabinogalactan