Abstract
An arabinogalactan of mean M(r) 2.2 x 10(6) has been isolated from the dried stems of Tinospora cordifolia and examined by methylation analysis, partial hydrolysis and carboxyl reduction. Purified polysaccharide showed polyclonal mitogenic activity against B-cells, their proliferation did not require macrophages.
MeSH terms
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Adjuvants, Immunologic / analysis
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Adjuvants, Immunologic / isolation & purification*
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Adjuvants, Immunologic / pharmacology*
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Animals
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Chromatography, Gel
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Galactans / analysis
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Galactans / isolation & purification*
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Galactans / pharmacology*
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Hydrolysis
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Medicine, Ayurvedic
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Methylation
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Mice
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Mitogens / analysis
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Mitogens / isolation & purification
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Mitogens / pharmacology
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Plant Extracts / analysis
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Plants, Medicinal / chemistry*
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Polysaccharides / analysis
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Polysaccharides / isolation & purification
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Polysaccharides / pharmacology
Substances
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Adjuvants, Immunologic
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Galactans
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Mitogens
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Plant Extracts
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Polysaccharides
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arabinogalactan