Outcome in patients with intracerebral hemorrhage: predictors of survival

Wien Klin Wochenschr. 2000 Feb 25;112(4):169-73.

Abstract

Background and purpose: The aim of this retrospective study was to determine in-hospital mortality and morbidity secondary to intracerebral hemorrhage and to analyse variables considered to be significantly associated with survival in these patients.

Patients and methods: The study cohort consisted of 135 consecutive patients with intracerebral hemorrhage, admitted to a large community hospital in the urban area of Vienna. The diagnosis of intracerebral hemorrhage was established in all cases with axial computed tomography. The following variables were analysed: age, sex, Glasgow coma score on admission, location of hematomas, intraventricular hemorrhage, neurosurgical interventions and medical complications.

Results: Sixty-seven (49.6%) of the 135 patients died, 50 (37%) of them during the first 4 days after the acute event, 13 within the 1st week and 4 within one month. In a multivariate analysis the risk of death was significantly increased by the presence of intraventricular hemorrhage (p < 0.01), a Glasgow coma score of 6 or less (p < 0.0001) and age greater than 60 years (p < 0.001). Gender, medical complications and surgical removal of hemorrhage with or without additional ventriculostomy did not correlate significantly with outcome while an infratentorial location of hematoma showed a trend (p < 0.15) towards a higher mortality.

Conclusion: A Glasgow coma score of 6 or less on admission, age greater than 60 years and the presence of intraventricular hemorrhage appear to be predictors of mortality in patients with intracerebral hemorrhage.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Brain / diagnostic imaging
  • Cerebral Hemorrhage / diagnosis
  • Cerebral Hemorrhage / mortality*
  • Cerebral Hemorrhage / surgery
  • Cohort Studies
  • Data Interpretation, Statistical
  • Female
  • Follow-Up Studies
  • Glasgow Coma Scale
  • Humans
  • Male
  • Middle Aged
  • Neurologic Examination
  • Outcome Assessment, Health Care
  • Retrospective Studies
  • Software
  • Time Factors
  • Tomography, X-Ray Computed