Objective: To summarize the clinical characteristics and treatment of vaginal clear cell carcinoma.
Methods: 3 cases of vaginal clear cell carcinoma admitted from 1958-1996 were analyzed retrospectively.
Results: Neither intrauterine diethylstilbestrol exposure nor diethylstibestrol use during their life was found in 3 cases. After external pelvic radiation and intracavitary 137Cs radiotherapy, 5-year survival was achieved in all 3 cases. 2 of them were alive with tumor free for 16 years.
Conclusion: The results suggested that the prognosis of vaginal clear cell carcinoma was rather good and it could be cured by proper radiotherapy.