Histological comparison of chronic hepatitis B and C in an Indian population

Trop Gastroenterol. 2000 Jan-Mar;21(1):20-1.

Abstract

Many studies have shown that steatosis, lymphoid aggregates or follicles and bile duct injury on histology are more consistently associated with chronic hepatitis C than chronic hepatitis B. We compared liver biopsies of 30 patients of chronic hepatitis B with an equal number of age matched patients with chronic hepatitis C. Steatosis, lymphoid aggregates or follicles and bile duct injury were noted in 66.6%, 36.6% and 26.6% cases respectively of chronic hepatitis B as compared to 70%, 33.3% and 30% cases respectively of chronic hepatitis C. Thus none of the features were considered distinctive of HCV infection.

MeSH terms

  • Adult
  • Biomarkers / blood
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Hepatitis Antibodies / blood
  • Hepatitis Antigens / blood
  • Hepatitis B, Chronic / immunology
  • Hepatitis B, Chronic / pathology*
  • Hepatitis C, Chronic / immunology
  • Hepatitis C, Chronic / pathology*
  • Humans
  • India
  • Male

Substances

  • Biomarkers
  • Hepatitis Antibodies
  • Hepatitis Antigens