Structural insights into clathrin-mediated endocytosis

Curr Opin Cell Biol. 2000 Aug;12(4):467-74. doi: 10.1016/s0955-0674(00)00118-6.

Abstract

The process of clathrin-mediated endocytosis from the plasma membrane has been the subject of many biological and biochemical investigations. Recent atomic resolution structures determined by X-ray crystallography now enable the molecular basis for the interactions of some components of the endocytic machinery to be understood in detail.

Publication types

  • Review

MeSH terms

  • Adaptor Protein Complex alpha Subunits
  • Adaptor Proteins, Vesicular Transport
  • Animals
  • Clathrin / chemistry*
  • Clathrin / metabolism*
  • Endocytosis / physiology*
  • Humans
  • Membrane Proteins / metabolism
  • Protein Conformation
  • Protein Structure, Tertiary
  • Structure-Activity Relationship

Substances

  • Adaptor Protein Complex alpha Subunits
  • Adaptor Proteins, Vesicular Transport
  • Clathrin
  • Membrane Proteins