Vertebral osteomyelitis caused by Streptococcus agalactiae

J Infect. 2000 Jul;41(1):84-90. doi: 10.1053/jinf.2000.0694.

Abstract

Streptococcus agalactiae is a rare cause of vertebral osteomyelitis. We present four cases of spondylitis caused by this micro-organism and a review of 20 cases previously described in the literature. Only seven patients (29%) were under 50 years of age. Diabetes mellitus and neoplasms were the most frequent underlying conditions, although 37.5% of the patients did not have any predisposition. Neck or back pain was the most common symptom. Diagnosis depended mainly on magnetic resonance imaging. Blood cultures were positive in 50% of the patients. The duration of antibiotic therapy was 6 weeks for most patients. The outcome was favourable, with none of the patients suffering serious sequelae.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abscess / microbiology
  • Aged
  • Amoxicillin-Potassium Clavulanate Combination / therapeutic use
  • Ampicillin / therapeutic use
  • Arthroplasty, Replacement, Hip
  • Cefazolin / therapeutic use
  • Cephalosporins / therapeutic use
  • Drug Therapy, Combination / therapeutic use
  • Female
  • Gentamicins / therapeutic use
  • Hemoglobins / analysis
  • Humans
  • Leukocyte Count
  • Lumbar Vertebrae / diagnostic imaging
  • MEDLINE
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Osteomyelitis / diagnosis*
  • Osteomyelitis / drug therapy
  • Penicillins / therapeutic use
  • Radiography
  • Spondylitis / diagnosis*
  • Spondylitis / drug therapy
  • Streptococcal Infections / blood
  • Streptococcal Infections / diagnosis*
  • Streptococcal Infections / drug therapy
  • Streptococcus agalactiae / drug effects
  • Streptococcus agalactiae / pathogenicity*

Substances

  • Cephalosporins
  • Gentamicins
  • Hemoglobins
  • Penicillins
  • Amoxicillin-Potassium Clavulanate Combination
  • Ampicillin
  • Cefazolin