Objective: To describe the distributions of the ambulatory blood pressure in a sample drawn from the Siberian population.
Methods: In the European Project On Genes in Hypertension (EPOGH), a random population sample of 162 persons (72 men and 90 women) was investigated in Novosibirsk, Russia. Mean age (+/-SD) was 40.6+/-15.3 years. Validated oscillometric 90207 SpaceLabs monitors were programmed to obtain ambulatory blood pressure readings at intervals of 15min from 0800h to 2200h and at 30min intervals from 2200h to 0800h. Daytime and nighttime were defined using short fixed-clock time intervals, which ranged from 1000h to 2000h and from midnight to 0600h, respectively.
Results: In the 162 participants, of whom 54 were hypertensive, 24-h clocktime day and clocktime night blood pressures averaged 120/73, 126/79 and 110/60mmHg, respectively. Compared with daytime values, blood pressures at the clinic were 5.7/1.1mmHg lower in 108 normotensive people, but 17.0/13.1mmHg higher in 54 hypertensive patients. In the normotensive subgroup, the 95th percentiles of the 24-h clocktime day and clocktime night blood pressures were 128/81, 136/86 and 118/72mmHg, respectively.
Conclusion: In comparison with other population surveys, the present interim report on the EPOGH study produced consistent results with respect to the distributions of the ambulatory measurements both in normotensive subjects and in the overall study population.