Administration of antisense oligodeoxyribonucleotides against mRNA of CD80 or CD86 prolongs survival of cardiac allografts by inhibition of CTL activity

Transplant Proc. 2001 Feb-Mar;33(1-2):551. doi: 10.1016/s0041-1345(00)02137-0.
No abstract available

MeSH terms

  • Animals
  • Antigens, CD / genetics*
  • B7-1 Antigen / genetics*
  • B7-2 Antigen
  • Graft Survival / drug effects*
  • Heart Transplantation / immunology
  • Heart Transplantation / physiology*
  • Membrane Glycoproteins / genetics*
  • Mice
  • Mice, Inbred C3H
  • Oligodeoxyribonucleotides, Antisense / therapeutic use*
  • RNA, Messenger / genetics*
  • T-Lymphocytes, Cytotoxic / drug effects*
  • T-Lymphocytes, Cytotoxic / immunology
  • Transplantation, Homologous

Substances

  • Antigens, CD
  • B7-1 Antigen
  • B7-2 Antigen
  • Cd86 protein, mouse
  • Membrane Glycoproteins
  • Oligodeoxyribonucleotides, Antisense
  • RNA, Messenger