PECAM-1 (CD31) engagement activates a phosphoinositide-independent, nonspecific cation channel in endothelial cells

FASEB J. 2001 May;15(7):1257-60. doi: 10.1096/fj.00-0467fje.

Authors

C D O'Brien¹, G Ji, Y X Wang, J Sun, V P Krymskaya, F L Ruberg, M I Kotlikoff, S M Albelda

Affiliation

¹ Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. christoo@mail.med.upenn.edu

PMID: 11344106
DOI: 10.1096/fj.00-0467fje

No abstract available

MeSH terms

Calcium / metabolism
Calcium Signaling*
Cations
Cells, Cultured
Endothelium, Vascular / cytology
Endothelium, Vascular / metabolism*
Humans
Ion Channel Gating
Ion Channels / metabolism*
Kinetics
Models, Biological
Patch-Clamp Techniques
Phosphatidylinositols / metabolism
Platelet Endothelial Cell Adhesion Molecule-1 / genetics
Platelet Endothelial Cell Adhesion Molecule-1 / metabolism*
Signal Transduction
Transfection

Substances

Cations
Ion Channels
Phosphatidylinositols
Platelet Endothelial Cell Adhesion Molecule-1
Calcium