The authors present a review of the literature on the etiology of epiphysiolysis of the hip and an original study on the hormone status of these patients. By examining eleven values including hormones, vector proteins, and hormonal transport, the authors related the data obtained to the anagraphical age of the patient, to his or her skeletal age, to the development of sexual features, and to the radiologic evidence of pathology. In light of the results obtained, despite the fact that the study only included 23 patients, the modified equilibrium between SHBG and Somatomedin C, would seem to lead to an accelerated turnover in the growth plate. The increase in BMI directly correlated with low levels of SHBG is also an indication of the increase in body weight that certainly contributes to slippage of the femoral head.