Cancer and hemopathy account from 4.5% to 14% of causes of intermittent fever (IF). The tumoral etiology is loss frequent in IF than continues fever. The man physiopathologic mechanism is represented by secretion of cytokines from tumour cells. IF may be the presenting symptom of cancer. This case diagnosis is usually made by cautions clinical evaluation and imaging. When cancer is known, IF can be related to infectious diseases or neoplastic evolution.